Percutaneous Transcatheter Aortic Disc Valve Prosthesis Implantation: A Feasibility Study
- Department of Cardiology, Institute for Clinical and Experimental Medicine, Videnska 1958/9, 140 21 Prague 4 (Czech Republic)
- Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Videnska 1958/9, 140 21 Prague 4 (Czech Republic)
- Dotter Interventional Institute, Oregon Health Sciences University, 3181 S.W. Jackson Park Road, L342, Portland, Oregon, 97201-3098 (United States)
Purpose: Over the past 30 years there have been experimental efforts at catheter-based management of aortic valve regurgitation with the idea of extending treatment to nonsurgical candidates. A new catheter-based aortic valve design is described.Methods: The new catheter-delivered valve consists of a stent-based valve cage with locking mechanism and a prosthetic flexible tilting valve disc. The valve cage is delivered first followed by deployment and locking of the disc. In acute experiments, valve implantation was done in four dogs.Results: Valve implantation was successful in all four animals. The implanted valve functioned well for the duration of the experiments (up to 3 hr).Conclusion: The study showed the implantation feasibility and short-term function of the tested catheter-based aortic disc valve. Further experimental studies are warranted.
- OSTI ID:
- 21083599
- Journal Information:
- Cardiovascular and Interventional Radiology, Vol. 23, Issue 5; Other Information: DOI: 10.1007/s002700010060; Copyright (c) 2000 Springer-Verlag New York Inc; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
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