Toxicity testing using Caenorhabditis elegans
- Georgia Institute of Technology, Atlanta, GA (United States)
- Univ. of Georgia, Athens, GA (United States)
Caenorhabditis elegans is a small free-living nematode that is representative of what may be the most abundant animal group. It has been promoted as a possible model organism for toxicity testing in the laboratory and in field evaluations in part because more is known about its biology than any other animal, Toxicity tests using C. elegans have been developed with lethality, reproduction, and behavior as end points. The tests have also been developed to varying degrees using standard laboratory media, water, and soil. The results of the tests when exposing C. elegans to a variety of metals, inorganic, and organic compounds indicate it is typically at least as sensitive as other species currently used, such as Daphnia and earthworms, and is generally much easier to maintain in the laboratory. The advantages and disadvantages of C. elegans and the state of development of the tests will be discussed.
- OSTI ID:
- 210299
- Report Number(s):
- CONF-9509139-; TRN: 95:008324-0140
- Resource Relation:
- Conference: 7. ACS special symposium: emerging technologies in hazardous waste management, Atlanta, GA (United States), 17-20 Sep 1995; Other Information: PBD: 1995; Related Information: Is Part Of Emerging technologies in hazardous waste management VII; Tedder, D.W. [ed.]; PB: 1352 p.
- Country of Publication:
- United States
- Language:
- English
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