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Title: Propagation based differential phase contrast imaging and tomography of murine tissue with a laser plasma x-ray source

Journal Article · · Applied Physics Letters
DOI:https://doi.org/10.1063/1.2802728· OSTI ID:21013749
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  1. Liver Research Center, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903 (United States)

An ultrafast, laser-driven x-ray source with a liquid mercury target has been used for phase contrast imaging of an excised murine liver and for computed tomography of an electronic component. The x-ray spectrum emitted at 5 kHz repetition rate is found to be similar to that of a 2.5 W, 30 kV microfocus x-ray tube with a tungsten anode. The images of the excised liver show the venous network with approximately 20 {mu}m spatial resolution. Phase contrast features in the tomographic images of the electronic component, transferred to the orthogonal cross sections upon reconstruction, show the internal components of the device with high contrast. Adequate signal-to-noise ratios in the images were achieved with exposure times between 1 and 3 min.

OSTI ID:
21013749
Journal Information:
Applied Physics Letters, Vol. 91, Issue 17; Other Information: DOI: 10.1063/1.2802728; (c) 2007 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6951
Country of Publication:
United States
Language:
English