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Title: Treatment of absolute painful glaucoma with dynamic arcs using novalis shaped beam radiosurgery

Journal Article · · International Journal of Radiation Oncology, Biology and Physics
 [1];  [2];  [2];  [3];  [2];  [2];  [2];  [2]
  1. Departamento de Neurooftalmologia, Instituto Nacional de Neurologia y Neurocirugia, Mexico DF (Mexico)
  2. Unidad de Radioneurocirugia, Instituto Nacional de Neurologia y Neurocirugia, Mexico DF (Mexico)
  3. Departamento de Neurocirugia, Instituto Nacional de Neurologia y Neurocirugia, Mexico DF (Mexico)

Purpose: We assessed the effect of shaped beam conformal stereotactic radiosurgery (SRS) in 1 patient with chronic painful glaucoma in one eye refractory to medical treatment. Methods and Materials: Left eye ciliary body was targeted at 18 Gy (90% isodose curve) with a dedicated linear accelerator (Novalis, BrainLAB, Germany) SRS. Interval follow-up was performed weekly for the first month, and every 2 months until 1 year was completed with clinical examinations and intraocular pressure (IOP) measurements. Results: Ocular pain resolved at 6 weeks after SRS treatment. IOP decreased and normalized at 1 year. Conclusions: We present a case in which SRS appears to be an effective treatment of chronic refractory painful glaucoma. Further Phase I studies are needed to know the best parameters for radiation dose, tolerance of organs at risk, and pathophysiologic effects.

OSTI ID:
20850194
Journal Information:
International Journal of Radiation Oncology, Biology and Physics, Vol. 66, Issue 4; Other Information: DOI: 10.1016/j.ijrobp.2006.04.060; PII: S0360-3016(06)02665-4; Copyright (c) 2006 Elsevier Science B.V., Amsterdam, Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
Country of Publication:
United States
Language:
English