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Title: Development of a four-dimensional image-guided radiotherapy system with a gimbaled X-ray head

Abstract

Purpose: To develop and evaluate a new four-dimensional image-guided radiotherapy system, which enables precise setup, real-time tumor tracking, and pursuit irradiation. Methods and Materials: The system has an innovative gimbaled X-ray head that enables small-angle ({+-}2.4{sup o}) rotations (pan and tilt) along the two orthogonal gimbals. This design provides for both accurate beam positioning at the isocenter by actively compensating for mechanical distortion and quick pursuit of the target. The X-ray head is composed of an ultralight C-band linear accelerator and a multileaf collimator. The gimbaled X-ray head is mounted on a rigid O-ring structure with an on-board imaging subsystem composed of two sets of kilovoltage X-ray tubes and flat panel detectors, which provides a pair of radiographs, cone beam computed tomography images useful for image guided setup, and real-time fluoroscopic monitoring for pursuit irradiation. Results: The root mean square accuracy of the static beam positioning was 0.1 mm for 360{sup o} of O-ring rotation. The dynamic beam response and positioning accuracy was {+-}0.6 mm for a 0.75 Hz, 40-mm stroke and {+-}0.4 mm for a 2.0 Hz, 8-mm stroke. The quality of the images was encouraging for using the tomography-based setup. Fluoroscopic images were sufficient for monitoring and trackingmore » lung tumors. Conclusions: Key functions and capabilities of our new system are very promising for precise image-guided setup and for tracking and pursuit irradiation of a moving target.« less

Authors:
 [1];  [1];  [2];  [3];  [1];  [1];  [3];  [3];  [4];  [3]
  1. Mitsubishi Heavy Industries, Ltd., Tokyo (Japan)
  2. Institute of Biomedical Research and Innovation, Kobe (Japan)
  3. Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto (Japan)
  4. Kyoto College of Medical Technology, Kyoto (Japan)
Publication Date:
OSTI Identifier:
20850081
Resource Type:
Journal Article
Journal Name:
International Journal of Radiation Oncology, Biology and Physics
Additional Journal Information:
Journal Volume: 66; Journal Issue: 1; Other Information: DOI: 10.1016/j.ijrobp.2006.04.044; PII: S0360-3016(06)00690-0; Copyright (c) 2006 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0360-3016
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; BEAMS; COLLIMATORS; COMPUTERIZED TOMOGRAPHY; DESIGN; HEAD; IMAGES; IRRADIATION; LINEAR ACCELERATORS; LUNGS; POSITIONING; RADIOTHERAPY; X RADIATION; X-RAY TUBES

Citation Formats

Kamino, Yuichiro, Takayama, Kenji, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Kokubo, Masaki, Narita, Yuichiro, Hirai, Etsuro, Kawawda, Noriyuki, Mizowaki, Takashi, Nagata, Yasushi, Nishidai, Takehiro, and Hiraoka, Masahiro. Development of a four-dimensional image-guided radiotherapy system with a gimbaled X-ray head. United States: N. p., 2006. Web. doi:10.1016/j.ijrobp.2006.04.044.
Kamino, Yuichiro, Takayama, Kenji, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Kokubo, Masaki, Narita, Yuichiro, Hirai, Etsuro, Kawawda, Noriyuki, Mizowaki, Takashi, Nagata, Yasushi, Nishidai, Takehiro, & Hiraoka, Masahiro. Development of a four-dimensional image-guided radiotherapy system with a gimbaled X-ray head. United States. https://doi.org/10.1016/j.ijrobp.2006.04.044
Kamino, Yuichiro, Takayama, Kenji, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Kokubo, Masaki, Narita, Yuichiro, Hirai, Etsuro, Kawawda, Noriyuki, Mizowaki, Takashi, Nagata, Yasushi, Nishidai, Takehiro, and Hiraoka, Masahiro. 2006. "Development of a four-dimensional image-guided radiotherapy system with a gimbaled X-ray head". United States. https://doi.org/10.1016/j.ijrobp.2006.04.044.
@article{osti_20850081,
title = {Development of a four-dimensional image-guided radiotherapy system with a gimbaled X-ray head},
author = {Kamino, Yuichiro and Takayama, Kenji and Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto and Kokubo, Masaki and Narita, Yuichiro and Hirai, Etsuro and Kawawda, Noriyuki and Mizowaki, Takashi and Nagata, Yasushi and Nishidai, Takehiro and Hiraoka, Masahiro},
abstractNote = {Purpose: To develop and evaluate a new four-dimensional image-guided radiotherapy system, which enables precise setup, real-time tumor tracking, and pursuit irradiation. Methods and Materials: The system has an innovative gimbaled X-ray head that enables small-angle ({+-}2.4{sup o}) rotations (pan and tilt) along the two orthogonal gimbals. This design provides for both accurate beam positioning at the isocenter by actively compensating for mechanical distortion and quick pursuit of the target. The X-ray head is composed of an ultralight C-band linear accelerator and a multileaf collimator. The gimbaled X-ray head is mounted on a rigid O-ring structure with an on-board imaging subsystem composed of two sets of kilovoltage X-ray tubes and flat panel detectors, which provides a pair of radiographs, cone beam computed tomography images useful for image guided setup, and real-time fluoroscopic monitoring for pursuit irradiation. Results: The root mean square accuracy of the static beam positioning was 0.1 mm for 360{sup o} of O-ring rotation. The dynamic beam response and positioning accuracy was {+-}0.6 mm for a 0.75 Hz, 40-mm stroke and {+-}0.4 mm for a 2.0 Hz, 8-mm stroke. The quality of the images was encouraging for using the tomography-based setup. Fluoroscopic images were sufficient for monitoring and tracking lung tumors. Conclusions: Key functions and capabilities of our new system are very promising for precise image-guided setup and for tracking and pursuit irradiation of a moving target.},
doi = {10.1016/j.ijrobp.2006.04.044},
url = {https://www.osti.gov/biblio/20850081}, journal = {International Journal of Radiation Oncology, Biology and Physics},
issn = {0360-3016},
number = 1,
volume = 66,
place = {United States},
year = {Fri Sep 01 00:00:00 EDT 2006},
month = {Fri Sep 01 00:00:00 EDT 2006}
}