Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities
- Department of Radiation Oncology, Seoul National University College of Medicine, Seoul (Korea, Republic of)
- Department of Radiation Oncology, Seoul National University College of Medicine, Seoul (Korea, Republic of) and Cancer Research Institute, Seoul National University College of Medicine, Seoul (Korea, Republic of) and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul (Korea, Republic of)
- Department of Pathology, Seoul National University College of Medicine, Seoul (Korea, Republic of)
Purpose: To evaluate the clinical outcome of Kimura's disease and to identify the optimal treatment regimen for Kimura's disease. Methods and Materials: Between 1984 and 2003, 14 patients with Kimura's disease were treated with radiotherapy (RT) and 9 patients were treated with local excision or systemic steroids. The radiation doses ranged from 20 to 45 Gy. Immunohistochemical studies were performed in 13 cases. Results: At RT completion, a marked response in terms of tumor size was noted in most cases. The median follow-up was 65 months. Local control was obtained in 9 (64.3%) of the 14 in the RT group and in 2 (22.2%) of the 9 in the non-RT group. No secondary malignancies were observed in the RT group. Conclusion: These results supports the finding that RT is more effective against Kimura's disease. Simple or immunohistochemical features did not influence the treatment outcome.
- OSTI ID:
- 20850002
- Journal Information:
- International Journal of Radiation Oncology, Biology and Physics, Vol. 65, Issue 4; Other Information: DOI: 10.1016/j.ijrobp.2006.02.024; PII: S0360-3016(06)00380-4; Copyright (c) 2006 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
- Country of Publication:
- United States
- Language:
- English
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