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Title: A computed tomography implementation of multiple-image radiography

Abstract

Conventional x-ray computed tomography (CT) produces a single volumetric image that represents the spatially variant linear x-ray attenuation coefficient of an object. However, in many situations, differences in the x-ray attenuation properties of soft tissues are very small and difficult to measure in conventional x-ray imaging. In this work, we investigate an analyzer-based imaging method, called computed tomography multiple-image radiography (CT-MIR), which is a tomographic implementation of the recently proposed multiple-image radiography method. The CT-MIR method reconstructs concurrently three physical properties of the object. In addition to x-ray attenuation, CT-MIR produces volumetric images that represent the refraction and ultrasmall-angle scattering properties of the object. These three images can provide a rich description of the object's physical properties that are revealed by the probing x-ray beam. An imaging model for CT-MIR that is based on the x-ray transform of the object properties is established. The CT-MIR method is demonstrated by use of experimental data acquired at a synchroton radiation imaging beamline, and is compared to the pre-existing diffraction-enhanced imaging CT method. We also investigate the merit of an iterative reconstruction method for use with future clinical implementations of CT-MIR, which we anticipate would be photon limited.

Authors:
; ; ; ; ; ;  [1]
  1. Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, Illinois 60616 (United States)
Publication Date:
OSTI Identifier:
20775051
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 33; Journal Issue: 2; Other Information: DOI: 10.1118/1.2150788; (c) 2006 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ATTENUATION; COMPUTERIZED TOMOGRAPHY; DIFFRACTION; IMAGE PROCESSING; IMAGES; IMPLEMENTATION; ITERATIVE METHODS; PHOTONS; PHYSICAL PROPERTIES; REFRACTION; SYNCHROTRON RADIATION

Citation Formats

Brankov, Jovan G, Wernick, Miles N, Yongyi, Yang, Jun, Li, Muehleman, Carol, Zhong, Zhong, Anastasio, Mark A, Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, Illinois 60616 and Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, Rush University Medical Center, Chicago, Illinois 60616, National Synchrotron Light Source, Brookhaven National Laboratory, Upton, New York 11973, and Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616. A computed tomography implementation of multiple-image radiography. United States: N. p., 2006. Web. doi:10.1118/1.2150788.
Brankov, Jovan G, Wernick, Miles N, Yongyi, Yang, Jun, Li, Muehleman, Carol, Zhong, Zhong, Anastasio, Mark A, Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, Illinois 60616 and Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, Rush University Medical Center, Chicago, Illinois 60616, National Synchrotron Light Source, Brookhaven National Laboratory, Upton, New York 11973, & Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616. A computed tomography implementation of multiple-image radiography. United States. https://doi.org/10.1118/1.2150788
Brankov, Jovan G, Wernick, Miles N, Yongyi, Yang, Jun, Li, Muehleman, Carol, Zhong, Zhong, Anastasio, Mark A, Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, Illinois 60616 and Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, Rush University Medical Center, Chicago, Illinois 60616, National Synchrotron Light Source, Brookhaven National Laboratory, Upton, New York 11973, and Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616. 2006. "A computed tomography implementation of multiple-image radiography". United States. https://doi.org/10.1118/1.2150788.
@article{osti_20775051,
title = {A computed tomography implementation of multiple-image radiography},
author = {Brankov, Jovan G and Wernick, Miles N and Yongyi, Yang and Jun, Li and Muehleman, Carol and Zhong, Zhong and Anastasio, Mark A and Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, Illinois 60616 and Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616 and Rush University Medical Center, Chicago, Illinois 60616 and National Synchrotron Light Source, Brookhaven National Laboratory, Upton, New York 11973 and Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616},
abstractNote = {Conventional x-ray computed tomography (CT) produces a single volumetric image that represents the spatially variant linear x-ray attenuation coefficient of an object. However, in many situations, differences in the x-ray attenuation properties of soft tissues are very small and difficult to measure in conventional x-ray imaging. In this work, we investigate an analyzer-based imaging method, called computed tomography multiple-image radiography (CT-MIR), which is a tomographic implementation of the recently proposed multiple-image radiography method. The CT-MIR method reconstructs concurrently three physical properties of the object. In addition to x-ray attenuation, CT-MIR produces volumetric images that represent the refraction and ultrasmall-angle scattering properties of the object. These three images can provide a rich description of the object's physical properties that are revealed by the probing x-ray beam. An imaging model for CT-MIR that is based on the x-ray transform of the object properties is established. The CT-MIR method is demonstrated by use of experimental data acquired at a synchroton radiation imaging beamline, and is compared to the pre-existing diffraction-enhanced imaging CT method. We also investigate the merit of an iterative reconstruction method for use with future clinical implementations of CT-MIR, which we anticipate would be photon limited.},
doi = {10.1118/1.2150788},
url = {https://www.osti.gov/biblio/20775051}, journal = {Medical Physics},
issn = {0094-2405},
number = 2,
volume = 33,
place = {United States},
year = {Wed Feb 15 00:00:00 EST 2006},
month = {Wed Feb 15 00:00:00 EST 2006}
}