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Title: Real-time DMLC IMRT delivery for mobile and deforming targets

Abstract

In numerous cases of radiotherapy delivery to moving targets, simplifying assumptions of identical pattern of motions of tissue for each fraction are not satisfied. Therefore, algorithms capable to respond in real time to motions of target registered at treatment should be developed to improve the precision of radiation intensity delivery. The DMLC delivery of predetermined intensity maps to moving and deforming targets in real time is developed in this paper. Algorithms are constructed so that constraints on maximum admissible speed of leaves are preserved during delivery. A sequence of examples is presented to illustrate behavior of leaf trajectories for representative cases of [dynamic multileaf collimator] (DMLC) [intensity modulated radiation therapy] (IMRT) real-time delivery. The examples presented show real-time deliveries to targets moving as rigid bodies and targets deforming uniformly over their volumes. Examples are admitting random perturbations of predefined target motions that are time dependent only, i.e., target motion perturbations are identical for all target points.

Authors:
; ;  [1]
  1. Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana 46202 (United States)
Publication Date:
OSTI Identifier:
20726252
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 32; Journal Issue: 9; Other Information: DOI: 10.1118/1.1987967; (c) 2005 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; ALGORITHMS; COLLIMATORS; MODULATION; RADIOTHERAPY; TIME DEPENDENCE

Citation Formats

Papiez, Lech, Rangaraj, Dharanipathy, Keall, Paul, and Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia. Real-time DMLC IMRT delivery for mobile and deforming targets. United States: N. p., 2005. Web. doi:10.1118/1.1987967.
Papiez, Lech, Rangaraj, Dharanipathy, Keall, Paul, & Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia. Real-time DMLC IMRT delivery for mobile and deforming targets. United States. https://doi.org/10.1118/1.1987967
Papiez, Lech, Rangaraj, Dharanipathy, Keall, Paul, and Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia. 2005. "Real-time DMLC IMRT delivery for mobile and deforming targets". United States. https://doi.org/10.1118/1.1987967.
@article{osti_20726252,
title = {Real-time DMLC IMRT delivery for mobile and deforming targets},
author = {Papiez, Lech and Rangaraj, Dharanipathy and Keall, Paul and Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia},
abstractNote = {In numerous cases of radiotherapy delivery to moving targets, simplifying assumptions of identical pattern of motions of tissue for each fraction are not satisfied. Therefore, algorithms capable to respond in real time to motions of target registered at treatment should be developed to improve the precision of radiation intensity delivery. The DMLC delivery of predetermined intensity maps to moving and deforming targets in real time is developed in this paper. Algorithms are constructed so that constraints on maximum admissible speed of leaves are preserved during delivery. A sequence of examples is presented to illustrate behavior of leaf trajectories for representative cases of [dynamic multileaf collimator] (DMLC) [intensity modulated radiation therapy] (IMRT) real-time delivery. The examples presented show real-time deliveries to targets moving as rigid bodies and targets deforming uniformly over their volumes. Examples are admitting random perturbations of predefined target motions that are time dependent only, i.e., target motion perturbations are identical for all target points.},
doi = {10.1118/1.1987967},
url = {https://www.osti.gov/biblio/20726252}, journal = {Medical Physics},
issn = {0094-2405},
number = 9,
volume = 32,
place = {United States},
year = {Thu Sep 15 00:00:00 EDT 2005},
month = {Thu Sep 15 00:00:00 EDT 2005}
}