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Title: Hypnotherapy in radiotherapy patients: A randomized trial

Journal Article · · International Journal of Radiation Oncology, Biology and Physics
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  1. Department of Radiotherapy, Academic Medical Centrum, University of Amsterdam, Amsterdam (Netherlands)
  2. Department of Psychology, Antoni van Leeuwenhoekziekenhuis, Netherlands Cancer Institute, Amsterdam (Netherlands)
  3. Department of Statistics, Antoni van Leeuwenhoekziekenhuis, Netherlands Cancer Institute, Amsterdam (Netherlands)

Purpose: To determine whether hypnotherapy reduces anxiety and improves the quality of life in cancer patients undergoing curative radiotherapy (RT). Methods and materials: After providing written informed consent, 69 patients were randomized between standard curative RT alone (36 controls) and RT plus hypnotherapy (33 patients). Patients in the hypnotherapy group received hypnotherapy at the intake, before RT simulation, before the first RT session, and halfway between the RT course. Anxiety was evaluated by the State-Trait Anxiety Inventory DY-1 form at six points. Quality of life was measured by the Rand Medical Outcomes Study 36-item Health Survey (SF-36) at five points. Additionally, patients answered a questionnaire to evaluate their experience and the possible benefits of this research project. Results: No statistically significant difference was found in anxiety or quality of life between the hypnotherapy and control groups. However, significantly more patients in the hypnotherapy group indicated an improvement in mental (p < 0.05) and overall (p < 0.05) well-being. Conclusion: Hypnotherapy did not reduce anxiety or improve the quality of life in cancer patients undergoing curative RT. The absence of statistically significant differences between the two groups contrasts with the hypnotherapy patients' own sense of mental and overall well-being, which was significantly greater after hypnotherapy. It cannot be excluded that the extra attention by the hypnotherapist was responsible for this beneficial effect in the hypnotherapy group. An attention-only control group would be necessary to control for this effect.

OSTI ID:
20633058
Journal Information:
International Journal of Radiation Oncology, Biology and Physics, Vol. 61, Issue 2; Other Information: DOI: 10.1016/j.ijrobp.2004.06.005; PII: S0360-3016(04)00968-X; Copyright (c) 2005 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
Country of Publication:
United States
Language:
English