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Title: Depth Profiling Of Small Molecule Ingress Into Planar and Cylindrical Materials Using NRA and PIXE

Journal Article · · AIP Conference Proceedings
DOI:https://doi.org/10.1063/1.1619763· OSTI ID:20632624
; ;  [1]
  1. Department of Physics, University of Surrey, Guildford, Surrey, GU2 7XH (United Kingdom)

The use of a 3He ion micro-beam technique to study the ingress/diffusion of water into a planar fibre optic grade glass and a cylindrical drug-release polymer is described. One-dimensional concentration profiles showing the depth of water ingress were produced. The depth of penetration of water into the glass was measured by fitting a gaussian function to the concentration profile. The ingress of water into the drug-release polymer was found to be Fickian and a cylindrical diffusion model used to obtain a diffusion coefficient.

OSTI ID:
20632624
Journal Information:
AIP Conference Proceedings, Vol. 680, Issue 1; Conference: 17. international conference on the application of accelerators in research and industry, Denton, TX (United States), 12-16 Nov 2002; Other Information: DOI: 10.1063/1.1619763; (c) 2003 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
Country of Publication:
United States
Language:
English