Experimental imaging and profiling of absorbed dose in phantoms exposed to epithermal neutron beams for neutron capture therapy
- Dipartimento di Fisica, Universita di Milano, Milan, (Italy)
Absorbed-dose images and depth-dose profiles have been measured in a tissue-equivalent phantom exposed to an epithermal neutron beam designed for neutron capture therapy. The spatial distribution of absorbed dose has been measured by means of gel dosimeters, imaged with optical analysis. From differential measurements with gels having different isotopic composition, the contributions of all the components of the neutron field have been separated. This separation is important, owing to the different biological effectiveness of the various kinds of emitted radiation. The doses coming from the reactions 1H(n,{gamma})2H and 14N(n,p)14C and the fast-neutron dose have been imaged. Moreover, a volume simulating a tumour with accumulation of 10B and/or 157Gd has been incorporated in the phantom and the doses due to the reactions with such isotopes have been imaged and profiled too. The results have been compared with those obtained with other experimental techniques and the agreement is very satisfactory.
- OSTI ID:
- 20632537
- Journal Information:
- AIP Conference Proceedings, Vol. 680, Issue 1; Conference: 17. international conference on the application of accelerators in research and industry, Denton, TX (United States), 12-16 Nov 2002; Other Information: DOI: 10.1063/1.1619900; (c) 2003 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
- Country of Publication:
- United States
- Language:
- English
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BORON 10
CARBON 14
DEPTH DOSE DISTRIBUTIONS
EPITHERMAL NEUTRONS
FAST NEUTRONS
GADOLINIUM 157
HYDROGEN 1 TARGET
ISOTOPE RATIO
NEOPLASMS
NEUTRON BEAMS
NEUTRON CAPTURE THERAPY
NEUTRON REACTIONS
NITROGEN 14
PHANTOMS
RADIATION DOSES
RADIATION MONITORING
SPATIAL DISTRIBUTION