A proposed procedure for derivation of regulatory values for carcinogenic airborne polycyclic aromatic hydrocarbons (PAHs) based on coal tar pitch (CTP) volatiles.
A procedure for estimating upper bound lifetime human cancer risk from air levels of six common carcinogenic polycyclic aromatic hydrocarbons (PAHs), termed APAHs of concern, is proposed. These PAHs are benzo(a)pyrene, benz(a)anthracene, benzo(b)fluoranthene, benzo(k)fluoranthene, indeno(1,2,3-c,d)pyrene, and chrysene. In application, this proposed procedure would regard any given air level obtained for a APAH of concern to originate from a standard mixture of coal tar pitch (CTP). The given air level for the APAHs of concern is then related to a corresponding air level of CTP and thence, to an inhalation unit cancer risk calculated for CTP. Reference values for the procedure are the relative and absolute PAH composition of a CTP standard (SRM-1597) and the inhalation unit cancer risk. Qualitative characterization of the results are a vital part of the procedure especially when more than one APAH of concern{at} is being considered. Toxic equivalency factors (TEFs) may be used as an evaluative tool in characterization of the procedure and outcome. Limitations of this proposed procedure include the uneven database for the reference values and the inability to consider air samples inclusive of another common carcinogenic PAH, dibenz(a,h)anthracene, due to its lack of documentation in CTP and high TEF
- Research Organization:
- Environmental Protection Agency, Research Triangle Park, NC (US)
- OSTI ID:
- 20002258
- Report Number(s):
- CONF-990608-; TRN: IM200002%%258
- Resource Relation:
- Conference: Air and Waste 92nd Annual Meeting and Exhibition, St. Louis, MO (US), 06/20/1999--06/24/1999; Other Information: 1 CD-ROM. Operating Systems: Windows 3.1, '95, '98 and NT; Macintosh; and UNIX; PBD: 1999; Related Information: In: Air and Waste 92nd annual meeting and exhibition proceedings, [9500] pages.
- Country of Publication:
- United States
- Language:
- English
Similar Records
Rapid, semimicro method for determination of polycyclic aromatic hydrocarbons in shellfish by automated gel permeation/liquid chromatography
Determination of polynuclear aromatic hydrocarbons in seafood by liquid chromatography with fluorescence detection