Osteosarcoma, seasonality, and environmental factors in Wisconsin, 1979-1989
- Eastman Dental Center, Rochester, NY (United States)
- Univ. of Wisconsin, Madison, WI (United States)
- Wisconsin Department of Health and Social Services, Madison, WI (United States); and others
Proxy exposure measures and readily available data from the Wisconsin Cancer Reporting System were used to contrast 167 osteosarcoma cases with 989 frequency-matched cancer referents reported during 1979-1989. Differences in potential exposure to water-borne radiation and fluoridated drinking water, population size for the listed place of residence, and seasonality were assessed. An association was found between osteosarcoma and residence in a population of less that 9000 (odds ratio = 1.6, 95% confidence interval = 1.1-2.4). In addition, an association between month of birth (May through July versus other months of birth) and osteosarcoma among individuals who were less than 25 y of age (odds ratio = 1.9, 95% confidence interval = 1.1-3.4). Overall, no association was found between potential exposure to fluoridated drinking water and osteosarcoma (odds ratio = 1.0, 95% confidence interval = 0.6-1.5). The association between osteosarcoma and water-borne radiation was weak and was not significant statistically (odds ratio = 1.5, 95% confidence interval = 0.8-2.8). 27 refs., 5 tabs.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 161660
- Journal Information:
- Archives of Environmental Health, Vol. 50, Issue 3; Other Information: PBD: May-Jun 1995
- Country of Publication:
- United States
- Language:
- English
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