Attachment of Metal Trications to Peptides

Journal Article · Mon Mar 01 00:00:00 EST 2004 · Journal of the American Society for Mass Spectrometry

DOI:https://doi.org/10.1016/j.jasms.2003.11.005· OSTI ID:15008850

Shvartsburg, Alexandre A; Jones, R C

Gas-phase complexes of triply charged metal ions with peptides may be readily produced using electrospray ionization, including for small peptides such as bradykinin and peptides with no basic residues such as insulin chain A. Attachment without charge-reduction is demonstrated for all trications studied: La3+, Al3+, Ga3+, Fe3+, V3+, and Cr3+. The intensities of adducts are often comparable to, or even exceed, those of protonated analogs in any charge state.

• Research Organization: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
• Sponsoring Organization: US Department of Energy (US)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 15008850
• Report Number(s): PNNL-SA-41474; KP1102010; TRN: US200427%%575
• Journal Information: Journal of the American Society for Mass Spectrometry, Vol. 15, Issue 3; Other Information: PBD: 1 Mar 2004
• Country of Publication: United States
• Language: English

Related Subjects

25 ENERGY STORAGE
ADDUCTS
BATTERY CHARGE STATE
BRADYKININ
INSULIN
IONIZATION
PEPTIDES
RESIDUES