Large Granular Lymphocytic (LGL) Leukemia in Rats Exposed to Intermittent 60 Hz Magnetic Fields

Journal Article · Sun Apr 01 00:00:00 EST 2001 · Bioelectromagnetics (New York)

DOI:https://doi.org/10.1002/bem.37· OSTI ID:15002313

Anderson, Larry E ^[1]; Morris, James E ^[1]; Miller, Douglas L ^[1]; Ebi, K L ^[2]; Sasser, Lyle B ^[1]

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1. BATTELLE (PACIFIC NW LAB)
2. Electric Power Research Institute

An animal model for large granular lymphocytic (LGL) leukemia in male Fischer 344 rats utilized to determine whether magnetic field exposure can be shown to influence the progression of leukemia. We previously reported that exposure to continuous 60 Hz 1 mT magnetic fields did not significantly alter the clinical progression of LGL leukemia in young male rats following inspection of spleen cells from donor leukemic rats. Results presented here extend those studies with the objectives to (1) replicate the previous study of continuous 60-Hz magnetic field exposures but using fewer LGL cells in the inoculum, and (2) determine if intermittent 60-Hz magnetic fields can alter the clinical progression of leukemia.

• Research Organization: Pacific Northwest National Lab., Richland, WA (US)
• Sponsoring Organization: US Department of Energy (US)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 15002313
• Report Number(s): PNWD-SA-5021; TRN: US200410%%25
• Journal Information: Bioelectromagnetics (New York), Vol. 22, Issue 3; Other Information: PBD: 1 Apr 2001; ISSN 0197-8462
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS
RATS
LEUKEMIA
MAGNETIC FIELDS
MALES
LYMPHATIC SYSTEM
60 HZ
CANCER
ANIMAL MODEL
CELL TRANSPLANTATION