Studies on the extended Techa river cohort: cancer risk estimation

Journal Article · Sat Dec 01 00:00:00 EST 2001 · Radiation and Environmental Biophysics

OSTI ID:15001457

Kossenko, M M ^[1]; Preston, D L ^[2]; Krestinina, L Y ^[1]; Degteva, M O ^[3]; Startsev, N V ^[1]; Thomas, T ^[4]; Vyushkova, O V ^[1]; Anspaugh, L R ^[5]; Napier, Bruce A ^[6]; Kozheurov, V P ^[3]; Ron, E ^[4]; Akleyev, A V ^[1]

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1. Urals Research Center for Radiation Medicine
2. Radiation Effects Research Foundation, 5-2 Hijiyama Park,
3. N/A
4. Division of Epidemiology and Genetics, National Cancer Institute,
5. Unknown
6. BATTELLE (PACIFIC NW LAB)

Initial population-based studies of riverside residents were begun in the late 1950s and in 1967 a systematic effort was undertaken to develop a well-defined fixed cohort of Techa river residents, to carry out ongoing mortality and (limited) clinical follow-up of this cohort, and to provide individualized dose estimates for cohort members. Over the past decade, extensive efforts have been made to refine the cohort definition and improve both the follow-up and dosimetry data. Analyses of the Techa river cohort can provide useful quantitative estimates of the effects of low dose rate, chronic external and internal exposures on cancer mortality and incidence and non-cancer mortality rates. These risk estimates complement quantitative risk estimates for acute exposures based on the atomic bomb survivors and chronic exposure risk estimates from worker studies, including Mayak workers and other groups with occupational radiation exposures. As the dosimetry and follow-up are refined it may also be possible to gain useful insights into risks associated with 90Sr exposures.

• Research Organization: Pacific Northwest National Lab., Richland, WA (US)
• Sponsoring Organization: US Department of Energy (US)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 15001457
• Report Number(s): PNNL-SA-31661; HD2006300; TRN: US200404%%186
• Journal Information: Radiation and Environmental Biophysics, Vol. 41, Issue 4; Other Information: PBD: 1 Dec 2001
• Country of Publication: United States
• Language: English

Related Subjects

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEFENSE
ACUTE EXPOSURE
CHRONIC EXPOSURE
DOSE RATES
DOSIMETRY
MORTALITY
NEOPLASMS
NUCLEAR WEAPONS
RADIATIONS
TECHA RIVER