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Title: Single photon emission computed tomography (SPECT) in epilepsy

Conference ·
OSTI ID:139694
 [1]
  1. Univ. of Texas Southwestern Medical School, Dallas (United States)

Epilepsy is a common neurologic disorder which has just begun to be studied with single photon emission computerized tomography (SPECT). Epilepsy usually is studied with electroencephalographic (EEG) techniques that demonstrate the physiologic changes that occur during seizures, and with neuroimaging techniques that show the brain structures where seizures originate. Neither method alone has been adequate to describe the pathophysiology of the patient with epilepsy. EEG techniques lack anatomic sensitivity, and there are no structural abnormalities shown by neuroimaging which are specific for epilepsy. Functional imaging (FI) has developed as a physiologic tool with anatomic sensitivity, and SPECT has been promoted as a FI technique because of its potentially wide availability. However, SPECT is early in its development and its clinical utility for epilepsy still has to be demonstrated. To understand this role of SPECT, consideration must be given to the pathophysiology of epilepsy, brain physiology, types of seizure, epileptic syndromes, and the SPECT technique itself. 44 refs., 2 tabs.

Research Organization:
Brookhaven National Lab. (BNL), Upton, NY (United States)
OSTI ID:
139694
Report Number(s):
CONF-9110368-; ON: TI92014827; TRN: 93:003237-012
Resource Relation:
Conference: Brain SPECT perfusion imaging: image acquisition, processing, display, and interpretation, Brookhaven, NY (United States), 8-9 Oct 1991; Other Information: PBD: [1991]; Related Information: Is Part Of Brain SPECT perfusion imaging: Image acquisition, processing, display, and interpretation; Weber, D.A.; Woodhead, A.D.; Vivirito, K.J. [eds.] [Brookhaven National Lab., Upton, NY (United States)]; Devous, M.D. Sr. [ed.] [Texas Univ., Dallas, TX (United States). Southwestern Medical Center]; Tikofsky, R.S. [ed.] [Medical Coll. of Wisconsin, Milwaukee, WI (United States)]; PB: 132 p.
Country of Publication:
United States
Language:
English

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