Association of apolipoprotein E allele {epsilon}4 with late-onset sporadic Alzheimer`s disease
Journal Article
·
· American Journal of Medical Genetics
- Regional Center of Neurogenetics, Reims (France); and others
Apolipoprotein E, type {epsilon}4 allele (ApoE {epsilon}4), is associated with late-onset sporadic Alzheimer`s disease (AD) in French patients. The association is highly significant (0.45 AD versus 0.12 controls for {epsilon}4 allele frequencies). These data support the involvement of ApoE {epsilon}4 allele as a very important risk factor for the clinical expression of AD. 22 refs., 1 fig., 3 tabs.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 135927
- Journal Information:
- American Journal of Medical Genetics, Vol. 54, Issue 3; Other Information: PBD: 15 Sep 1994
- Country of Publication:
- United States
- Language:
- English
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