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Title: X-Ray Laser Gets First Real-Time Snapshots of a Chemical Flipping a Biological Switch

Scientists have used the powerful X-ray laser at the Department of Energy’s SLAC National Accelerator Laboratory to make the first snapshots of a chemical interaction between two biomolecules – one that flips an RNA “switch” that regulates production of proteins, the workhorse molecules of life. The results, published in Nature, show the game-changing potential of X-ray free-electron lasers, or XFELs, for studying RNA, which guides protein manufacturing in the cell, serves as the primary genetic material in retroviruses such as HIV and also plays a role in most forms of cancer.
Publication Date:
OSTI Identifier:
1333680
Resource Type:
Other
Research Org:
SLAC (SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States))
Sponsoring Org:
USDOE Office of Science (SC)
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES RNA; RIBONUCLEIC ACID; X-RAY; BIOCHEMICAL INTERACTION; CHEMICAL INTERACTION