Methods of treating Parkinson's disease using viral vectors

Bankiewicz, Krystof; Cunningham, Janet

Title: Methods of treating Parkinson's disease using viral vectors

Patent · Tue Nov 15 00:00:00 EST 2016

OSTI ID:1332285

Bankiewicz, Krystof; Cunningham, Janet

Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC03-76SF00098; AC02-05CH11231

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 9,492,415

Application Number:: 13/647,155

OSTI ID:: 1332285

Resource Relation:: Patent File Date: 2012 Oct 08

Country of Publication:: United States

Language:: English

References (32)

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