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Title: Methods of treating Parkinson's disease using viral vectors

Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.
Authors:
;
Publication Date:
OSTI Identifier:
1332285
Report Number(s):
9,492,415
13/647,155
DOE Contract Number:
AC03-76SF00098; AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Oct 08
Research Org:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES