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Title: Chip-based device for parallel sorting, amplification, detection, and identification of nucleic acid subsequences

Abstract

An apparatus for chip-based sorting, amplification, detection, and identification of a sample having a planar substrate. The planar substrate is divided into cells. The cells are arranged on the planar substrate in rows and columns. Electrodes are located in the cells. A micro-reactor maker produces micro-reactors containing the sample. The micro-reactor maker is positioned to deliver the micro-reactors to the planar substrate. A microprocessor is connected to the electrodes for manipulating the micro-reactors on the planar substrate. A detector is positioned to interrogate the sample contained in the micro-reactors.

Inventors:
;
Publication Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1289941
Patent Number(s):
9,409,177
Application Number:
12/401,714
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2009 Mar 11
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 47 OTHER INSTRUMENTATION

Citation Formats

Beer, Neil Reginald, and Colston, Jr, Billy W. Chip-based device for parallel sorting, amplification, detection, and identification of nucleic acid subsequences. United States: N. p., 2016. Web.
Beer, Neil Reginald, & Colston, Jr, Billy W. Chip-based device for parallel sorting, amplification, detection, and identification of nucleic acid subsequences. United States.
Beer, Neil Reginald, and Colston, Jr, Billy W. 2016. "Chip-based device for parallel sorting, amplification, detection, and identification of nucleic acid subsequences". United States. https://www.osti.gov/servlets/purl/1289941.
@article{osti_1289941,
title = {Chip-based device for parallel sorting, amplification, detection, and identification of nucleic acid subsequences},
author = {Beer, Neil Reginald and Colston, Jr, Billy W.},
abstractNote = {An apparatus for chip-based sorting, amplification, detection, and identification of a sample having a planar substrate. The planar substrate is divided into cells. The cells are arranged on the planar substrate in rows and columns. Electrodes are located in the cells. A micro-reactor maker produces micro-reactors containing the sample. The micro-reactor maker is positioned to deliver the micro-reactors to the planar substrate. A microprocessor is connected to the electrodes for manipulating the micro-reactors on the planar substrate. A detector is positioned to interrogate the sample contained in the micro-reactors.},
doi = {},
url = {https://www.osti.gov/biblio/1289941}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 09 00:00:00 EDT 2016},
month = {Tue Aug 09 00:00:00 EDT 2016}
}

Works referenced in this record:

Droplet-based chemistry on a programmable micro-chip
journal, January 2004


Dielectrophoresis-based programmable fluidic processors
journal, January 2004