Anomalous partitioning of water in coexisting liquid phases of lipid multilayers near 100% relative humidity

Journal Article · Mon Nov 30 00:00:00 EST 2015 · Physical Chemistry Chemical Physics. PCCP (Print)

DOI:https://doi.org/10.1039/C5CP04703J· OSTI ID:1287330

Ma, Yicong; Ghosh, Sajal K.; Bera, Sambhunath; Jiang, Zhang; Schlepütz, Christian M.; Karapetrova, Evguenia; Lurio, Laurence B.; Sinha, Sunil K.

X-ray diffraction is used to determine the hydration dependence of a ternary mixture lipid multilayer structure which has phase separated into liquid-ordered (Lo) and liquid-disordered (Ld) phases. An anomaly is observed in the swelling behavior of the Ld phase at a relative humidity (RH) close to 100%, which is different from the anomalous swelling happens close to the main lipid gel-fluid transition. The lamellar repeat distance of the Ld phase swells by an extra 4 Å, well beyond the equilibrium spacing predicted by the inter-bilayer forces. This anomalous swelling is caused by the hydrophobic mismatch energy at the domain boundaries, which produces surprisingly long range effect.

• Research Organization: Argonne National Lab. (ANL), Argonne, IL (United States)
• Sponsoring Organization: USDOE Office of Science (SC), Basic Energy Sciences (BES)
• DOE Contract Number: AC02-06CH11357
• OSTI ID: 1287330
• Journal Information: Physical Chemistry Chemical Physics. PCCP (Print), Vol. 18, Issue 2; ISSN 1463-9076
• Publisher: Royal Society of Chemistry
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
X-ray
anomalous swelling
full hydration
humidity chamber
membrane
multilayer
phase separation
ternary mixture