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Title: Perspectives on West Africa Ebola Virus Disease Outbreak, 2013-2016

The variety of factors that contributed to the initial undetected spread of Ebola virus disease in West Africa during 2013-2016 and the difficulty controlling the outbreak once the etiology was identified highlight priorities for disease prevention, detection, and response. These factors include occurrence in a region recovering from civil instability and lacking experience with Ebola response; inadequate surveillance, recognition of suspected cases, and Ebola diagnosis; mobile populations and extensive urban transmission; and the community's insufficient general understanding about the disease. The magnitude of the outbreak was not attributable to a substantial change of the virus. Finally, continued efforts during the outbreak and in preparation for future outbreak response should involve identifying the reservoir, improving in-country detection and response capacity, conducting survivor studies and supporting survivors, engaging in culturally appropriate public education and risk communication, building productive interagency relationships, and continuing support for basic research.
 [1] ;  [1] ;  [1] ;  [1] ;  [1]
  1. Centers for Disease Control and Prevention (CDC), Atlanta, GA (United States)
Publication Date:
OSTI Identifier:
Accepted Manuscript
Journal Name:
Emerging Infectious Diseases
Additional Journal Information:
Journal Volume: 22; Journal Issue: 6; Journal ID: ISSN 1080-6040
Centers for Disease Control and Prevention
Research Org:
Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN (United States)
Sponsoring Org:
USDOE; Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN (United States); National Institutes of Health (NIH)
Country of Publication:
United States
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES bats rousettus-aegyptiacus; marburg hemorrhagic-fever; fruit bats; transmission; prevalence; reservoirs; evolution; sequences; guinea; uganda