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Title: Genome-scale resources for Thermoanaerobacterium saccharolyticum

Journal Article · · BMC Systems Biology
 [1];  [2];  [3];  [4];  [4];  [4];  [1];  [4];  [4];  [4];  [4];  [4];  [5];  [1];  [6];  [7];  [4];  [4];  [1];  [8]
  1. Mascoma Corporation, Lebanon, NH (United States)
  2. Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dow AgroSciences, Indianapolis, IN (United States)
  3. Virginia Commonwealth Univ., Richmond, VA (United States); Univ. of Toronto, ON (Canada)
  4. Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
  5. Mascoma Corporation, Lebanon, NH (United States); Novogy Inc, Cambridge, MA (United States)
  6. Mascoma Corporation, Lebanon, NH (United States) ; Dartmouth College, Hanover, NH (United States)
  7. Virginia Commonwealth Univ., Richmond, VA (United States)
  8. Mascoma Corporation, Lebanon, NH (United States); Dartmouth College, Hanover, NH (United States)

Thermoanaerobacterium saccharolyticum is a hemicellulose-degrading thermophilic anaerobe that was previously engineered to produce ethanol at high yield. For this research, a major project was undertaken to develop this organism into an industrial biocatalyst, but the lack of genome information and resources were recognized early on as a key limitation.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). BioEnergy Science Center (BESC)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
AC05-00OR22725
OSTI ID:
1265410
Journal Information:
BMC Systems Biology, Vol. 9, Issue 1; ISSN 1752-0509
Publisher:
BioMed CentralCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 13 works
Citation information provided by
Web of Science

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Cited By (5)

Integrated omics analyses reveal the details of metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass journal January 2017
BiKEGG: a COBRA toolbox extension for bridging the BiGG and KEGG databases journal January 2016
A Link Between Plasma Microbial Translocation, Microbiome, and Autoantibody Development in First‐Degree Relatives of Systemic Lupus Erythematosus Patients journal September 2019
The redox-sensing protein Rex modulates ethanol production in Thermoanaerobacterium saccharolyticum journal April 2018
Strain and bioprocess improvement of a thermophilic anaerobe for the production of ethanol from wood journal June 2016