Spectroscopic microscopy as a powerful tool for the assessment of dermal exposure to pesticides and environmental pollutants
- Texas Southern Univ., Houston, TX (United States)
- EPA, Las Vegas, NV (United States)
FTIR Microscopy and Computerized Video Optical Imaging in Ultraviolet Induced Visible fluorescence Techniques were used to study the behavior of malathion and deltamethrin through die skin layers of rats exposed to dermal doses of the individual insecticide. The technique was also shown to be useful for monitoring penetration of pesticide through protective clothing and therefore may serve as a straight forward direct tool for assessing human dermal exposure to pesticides. One advantage of this techniques is the ability to detect both parent compounds and their metabolites by scanning for the desired wave numbers in the IR spectra or by controlling excitation and emission wavelengths. The technique was also compared to microscopic autoradiography where the skin was treated with radioactive malathion and distribution of the radioactivity was located by gel X Ray film on the microscope slide.
- OSTI ID:
- 126058
- Report Number(s):
- CONF-950402-; TRN: 95:006086-0026
- Resource Relation:
- Conference: 209. American Chemical Society (ACS) national meeting, Anaheim, CA (United States), 2-6 Apr 1995; Other Information: PBD: 1995; Related Information: Is Part Of 209th ACS national meeting; PB: 2088 p.
- Country of Publication:
- United States
- Language:
- English
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