Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism"

Li, Fei; Liu, Jian; Zheng, Yi; Garavito, R. Michael; Ferguson-Miller, Shelagh

doi:10.1126/science.aab2595

Title: Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism"

Journal Article · Thu Oct 29 00:00:00 EDT 2015 · Science

DOI:https://doi.org/10.1126/science.aab2595· OSTI ID:1252754

Li, Fei ^[1]; Liu, Jian ^[1]; Zheng, Yi ^[1]; Garavito, R. Michael ^[1]; Ferguson-Miller, Shelagh ^[1]

Univ. of California, San Diego, CA (United States)

Wang comments that the diffraction data for the structure of the A139T mutant of translocator protein TSPO from Rhodobacter sphaeroides should be used to 1.65 instead of 1.8 angstroms and that the density interpreted as porphyrin and monoolein is better fitted as polyethylene glycol. Although different practices of data processing exist, in this case they do not substantially influence the final map. Additional data are presented supporting the fit of a porphyrin and monooleins.

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Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

OSTI ID:: 1252754

Journal Information:: Science, Vol. 350, Issue 6260; ISSN 0036-8075

Publisher:: AAASCopyright Statement

Country of Publication:: United States

Language:: ENGLISH

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Cited by: 12 works

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References (11)

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