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Title: Structural basis for the blockade of MATE multidrug efflux pumps

Journal Article · · Nature Communications
DOI:https://doi.org/10.1038/ncomms8995· OSTI ID:1245872

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
UNIVERSITY
OSTI ID:
1245872
Journal Information:
Nature Communications, Vol. 6, Issue 7995; ISSN 2041-1723
Country of Publication:
United States
Language:
ENGLISH

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Cited By (18)

Structural basis for xenobiotic extrusion by eukaryotic MATE transporter journal November 2017
Multidrug efflux pumps: structure, function and regulation journal July 2018
Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor journal December 2017
Broadly conserved Na + -binding site in the N-lobe of prokaryotic multidrug MATE transporters journal June 2018
Sodium and proton coupling in the conformational cycle of a MATE antiporter from Vibrio cholerae journal June 2018
Inward-facing conformation of a multidrug resistance MATE family transporter journal June 2019
The N-terminal domain of an archaeal multidrug and toxin extrusion (MATE) transporter mediates proton coupling required for prokaryotic drug resistance journal July 2019
Tackling drug resistance with efflux pump inhibitors: from bacteria to cancerous cells journal April 2019
Structures of multidrug and toxic compound extrusion transporters and their mechanistic implications journal January 2016
The multitasking abilities of MATE transporters in plants journal May 2019
Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor journal August 2017
Pacing across the membrane: the novel PACE family of efflux pumps is widespread in Gram-negative pathogens journal September 2018
Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition journal June 2019
The putative drug efflux systems of the Bacillus cereus group journal May 2017
Genomic and phenotypic characterisation of fluoroquinolone resistance mechanisms in Enterobacteriaceae in Durban, South Africa journal June 2017
Carbonyl Cyanide m-Chlorophenylhydrazine (CCCP) Reverses Resistance to Colistin, but Not to Carbapenems and Tigecycline in Multidrug-Resistant Enterobacteriaceae journal February 2017
Efflux pump inhibitors for bacterial pathogens: From bench to bedside journal January 2019
Lipid Flippases for Bacterial Peptidoglycan Biosynthesis journal January 2015

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