Chiral recognition and selection during the self-assembly process of protein-mimic macroanions
Abstract
The research on chiral recognition and chiral selection is not only fundamental in resolving the puzzle of homochirality, but also instructive in chiral separation and stereoselective catalysis. Here we report the chiral recognition and chiral selection during the self-assembly process of two enantiomeric wheel-shaped macroanions, [Fe28(μ3-O)8(Tart)16(HCOO)24]20- (Tart=D- or L-tartaric acid tetra-anion). The enantiomers are observed to remain self-sorted and self-assemble into their individual assemblies in their racemic mixture solution. The addition of chiral co-anions can selectively suppress the self-assembly process of the enantiomeric macroanions, which is further used to separate the two enantiomers from their mixtures on the basis of the size difference between the monomers and the assemblies. We believe that delicate long-range electrostatic interactions could be responsible for such high-level chiral recognition and selection.
- Authors:
- Publication Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE Office of Science - Office of Basic Energy Sciences - Scientific User Facilities Division; National Science Foundation (NSF); National Natural Science Foundation of China (NSFC)
- OSTI Identifier:
- 1239600
- DOE Contract Number:
- AC02-06CH11357
- Resource Type:
- Journal Article
- Journal Name:
- Nature Communications
- Additional Journal Information:
- Journal Volume: 6; Journal ID: ISSN 2041-1723
- Publisher:
- Nature Publishing Group
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Yin, Panchao, Zhang, Zhi-Ming, Lv, Hongjin, Li, Tao, Haso, Fadi, Hu, Lang, Zhang, Baofang, Basca, John, Wei, Yongge, Gao, Yanqing, Hou, Yu, Li, Yang-Guang, Hill, Craig L., Wang, En-Bo, and Liu, Tianbo. Chiral recognition and selection during the self-assembly process of protein-mimic macroanions. United States: N. p., 2015.
Web. doi:10.1038/ncomms7475.
Yin, Panchao, Zhang, Zhi-Ming, Lv, Hongjin, Li, Tao, Haso, Fadi, Hu, Lang, Zhang, Baofang, Basca, John, Wei, Yongge, Gao, Yanqing, Hou, Yu, Li, Yang-Guang, Hill, Craig L., Wang, En-Bo, & Liu, Tianbo. Chiral recognition and selection during the self-assembly process of protein-mimic macroanions. United States. https://doi.org/10.1038/ncomms7475
Yin, Panchao, Zhang, Zhi-Ming, Lv, Hongjin, Li, Tao, Haso, Fadi, Hu, Lang, Zhang, Baofang, Basca, John, Wei, Yongge, Gao, Yanqing, Hou, Yu, Li, Yang-Guang, Hill, Craig L., Wang, En-Bo, and Liu, Tianbo. 2015.
"Chiral recognition and selection during the self-assembly process of protein-mimic macroanions". United States. https://doi.org/10.1038/ncomms7475.
@article{osti_1239600,
title = {Chiral recognition and selection during the self-assembly process of protein-mimic macroanions},
author = {Yin, Panchao and Zhang, Zhi-Ming and Lv, Hongjin and Li, Tao and Haso, Fadi and Hu, Lang and Zhang, Baofang and Basca, John and Wei, Yongge and Gao, Yanqing and Hou, Yu and Li, Yang-Guang and Hill, Craig L. and Wang, En-Bo and Liu, Tianbo},
abstractNote = {The research on chiral recognition and chiral selection is not only fundamental in resolving the puzzle of homochirality, but also instructive in chiral separation and stereoselective catalysis. Here we report the chiral recognition and chiral selection during the self-assembly process of two enantiomeric wheel-shaped macroanions, [Fe28(μ3-O)8(Tart)16(HCOO)24]20- (Tart=D- or L-tartaric acid tetra-anion). The enantiomers are observed to remain self-sorted and self-assemble into their individual assemblies in their racemic mixture solution. The addition of chiral co-anions can selectively suppress the self-assembly process of the enantiomeric macroanions, which is further used to separate the two enantiomers from their mixtures on the basis of the size difference between the monomers and the assemblies. We believe that delicate long-range electrostatic interactions could be responsible for such high-level chiral recognition and selection.},
doi = {10.1038/ncomms7475},
url = {https://www.osti.gov/biblio/1239600},
journal = {Nature Communications},
issn = {2041-1723},
number = ,
volume = 6,
place = {United States},
year = {Sun Mar 01 00:00:00 EST 2015},
month = {Sun Mar 01 00:00:00 EST 2015}
}