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Title: Chiral recognition and selection during the self-assembly process of protein-mimic macroanions

Abstract

The research on chiral recognition and chiral selection is not only fundamental in resolving the puzzle of homochirality, but also instructive in chiral separation and stereoselective catalysis. Here we report the chiral recognition and chiral selection during the self-assembly process of two enantiomeric wheel-shaped macroanions, [Fe28(μ3-O)8(Tart)16(HCOO)24]20- (Tart=D- or L-tartaric acid tetra-anion). The enantiomers are observed to remain self-sorted and self-assemble into their individual assemblies in their racemic mixture solution. The addition of chiral co-anions can selectively suppress the self-assembly process of the enantiomeric macroanions, which is further used to separate the two enantiomers from their mixtures on the basis of the size difference between the monomers and the assemblies. We believe that delicate long-range electrostatic interactions could be responsible for such high-level chiral recognition and selection.

Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE Office of Science - Office of Basic Energy Sciences - Scientific User Facilities Division; National Science Foundation (NSF); National Natural Science Foundation of China (NSFC)
OSTI Identifier:
1239600
DOE Contract Number:  
AC02-06CH11357
Resource Type:
Journal Article
Journal Name:
Nature Communications
Additional Journal Information:
Journal Volume: 6; Journal ID: ISSN 2041-1723
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
English

Citation Formats

Yin, Panchao, Zhang, Zhi-Ming, Lv, Hongjin, Li, Tao, Haso, Fadi, Hu, Lang, Zhang, Baofang, Basca, John, Wei, Yongge, Gao, Yanqing, Hou, Yu, Li, Yang-Guang, Hill, Craig L., Wang, En-Bo, and Liu, Tianbo. Chiral recognition and selection during the self-assembly process of protein-mimic macroanions. United States: N. p., 2015. Web. doi:10.1038/ncomms7475.
Yin, Panchao, Zhang, Zhi-Ming, Lv, Hongjin, Li, Tao, Haso, Fadi, Hu, Lang, Zhang, Baofang, Basca, John, Wei, Yongge, Gao, Yanqing, Hou, Yu, Li, Yang-Guang, Hill, Craig L., Wang, En-Bo, & Liu, Tianbo. Chiral recognition and selection during the self-assembly process of protein-mimic macroanions. United States. https://doi.org/10.1038/ncomms7475
Yin, Panchao, Zhang, Zhi-Ming, Lv, Hongjin, Li, Tao, Haso, Fadi, Hu, Lang, Zhang, Baofang, Basca, John, Wei, Yongge, Gao, Yanqing, Hou, Yu, Li, Yang-Guang, Hill, Craig L., Wang, En-Bo, and Liu, Tianbo. 2015. "Chiral recognition and selection during the self-assembly process of protein-mimic macroanions". United States. https://doi.org/10.1038/ncomms7475.
@article{osti_1239600,
title = {Chiral recognition and selection during the self-assembly process of protein-mimic macroanions},
author = {Yin, Panchao and Zhang, Zhi-Ming and Lv, Hongjin and Li, Tao and Haso, Fadi and Hu, Lang and Zhang, Baofang and Basca, John and Wei, Yongge and Gao, Yanqing and Hou, Yu and Li, Yang-Guang and Hill, Craig L. and Wang, En-Bo and Liu, Tianbo},
abstractNote = {The research on chiral recognition and chiral selection is not only fundamental in resolving the puzzle of homochirality, but also instructive in chiral separation and stereoselective catalysis. Here we report the chiral recognition and chiral selection during the self-assembly process of two enantiomeric wheel-shaped macroanions, [Fe28(μ3-O)8(Tart)16(HCOO)24]20- (Tart=D- or L-tartaric acid tetra-anion). The enantiomers are observed to remain self-sorted and self-assemble into their individual assemblies in their racemic mixture solution. The addition of chiral co-anions can selectively suppress the self-assembly process of the enantiomeric macroanions, which is further used to separate the two enantiomers from their mixtures on the basis of the size difference between the monomers and the assemblies. We believe that delicate long-range electrostatic interactions could be responsible for such high-level chiral recognition and selection.},
doi = {10.1038/ncomms7475},
url = {https://www.osti.gov/biblio/1239600}, journal = {Nature Communications},
issn = {2041-1723},
number = ,
volume = 6,
place = {United States},
year = {Sun Mar 01 00:00:00 EST 2015},
month = {Sun Mar 01 00:00:00 EST 2015}
}