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Title: Nickel Superoxide Dismutase: Structural and Functional Roles of His1 and Its H-Bonding Network

Journal Article · · Biochemistry
DOI:https://doi.org/10.1021/bi501258u· OSTI ID:1229241

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
DOE Contract Number:
SC00112704
OSTI ID:
1229241
Report Number(s):
BNL-111316-2015-JA
Journal Information:
Biochemistry, Vol. 54, Issue 4; ISSN 0006-2960
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
English

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Nickel superoxide dismutase: structural and functional roles of Cys2 and Cys6 journal March 2010
Metallopeptide Based Mimics with Substituted Histidines Approximate a Key Hydrogen Bonding Network in the Metalloenzyme Nickel Superoxide Dismutase journal November 2009
Role of Conserved Tyrosine Residues in NiSOD Catalysis: A Case of Convergent Evolution journal March 2009
Probing Variable Axial Ligation in Nickel Superoxide Dismutase Utilizing Metallopeptide-Based Models:  Insight into the Superoxide Disproportionation Mechanism journal November 2007
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Crystal structure of nickel-containing superoxide dismutase reveals another type of active site journal June 2004
Free radicals, metals and antioxidants in oxidative stress-induced cancer journal March 2006
Spectroscopic and Computational Studies of Ni Superoxide Dismutase:  Electronic Structure Contributions to Enzymatic Function journal April 2005
Examination of the Nickel Site Structure and Reaction Mechanism in Streptomyces seoulensis Superoxide Dismutase journal March 1999
Real-space multiple-scattering calculation and interpretation of x-ray-absorption near-edge structure journal September 1998
Spectroscopic and computational investigation of three Cys-to-Ser mutants of nickel superoxide dismutase: insight into the roles played by the Cys2 and Cys6 active-site residues journal March 2010
Reactivity of HO 2 /O 2 Radicals in Aqueous Solution
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Expression, Reconstitution, and Mutation of Recombinant Streptomyces c oelicolor NiSOD journal January 2004
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Immobilized Metal Complexes in Porous Organic Hosts:  Development of a Material for the Selective and Reversible Binding of Nitric Oxide journal February 2001
Redox Tuning over Almost 1 V in a Structurally Conserved Active Site: Lessons from Fe-Containing Superoxide Dismutase journal April 2008
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SIXPack a Graphical User Interface for XAS Analysis Using IFEFFIT journal January 2005
Nickel-Specific Response in the Transcriptional Regulator, Escherichia coli NikR journal April 2007
A Nickel Superoxide Dismutase Maquette That Reproduces the Spectroscopic and Functional Properties of the Metalloenzyme journal March 2006
Use of a Metallopeptide-Based Mimic Provides Evidence for a Proton-Coupled Electron-Transfer Mechanism for Superoxide Reduction by Nickel-Containing Superoxide Dismutase journal January 2013
Superoxide Dismutases and Superoxide Reductases journal January 2014
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Cited By (6)

Thione-Based Nickel(II) Complexes as Functional Antioxidant Mimics: Scavenging Activity of Reactive Oxygen Species O2 −· and X-Ray Crystal Structure of [Ni(Ttxyly)2]2 {Ttxylyl = Hydrotris(2-mercapto-1-xylyl-imidazolyl)borate} journal May 2017
pH Dependent Reversible Formation of a Binuclear Ni2 Metal-Center within a Peptide Scaffold journal July 2019
Insights into the dioxygen activation and catalytic mechanism of the nickel-containing quercetinase journal January 2018
Spectroscopically Characterized Synthetic Mononuclear Nickel-Oxygen Species journal August 2016
Ni II Complex Formation and Protonation States at the Active Site of a Nickel Superoxide Dismutase-Derived Metallopeptide: Implications for the Mechanism of Superoxide Degradation journal September 2018
Integrative Metabolomic and Metallomic Analysis in a Case–Control Cohort With Parkinson’s Disease journal December 2019

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