Crystallization of Lysozyme with (R)-, (S)- and (RS)-2-methyl-2,4-pentanediol

Stauber, M; Jakoncic, J; Berger, J; Karp, J; Axelbaum, A; Sastow, D; Buldyrev, S; Hrnjez, B; Asherie, J

doi:10.1107/S1399004714025061

Title: Crystallization of Lysozyme with (R)-, (S)- and (RS)-2-methyl-2,4-pentanediol

Journal Article · Sun Mar 01 00:00:00 EST 2015 · Acta Crystallographica. Section D: Biological Crystallography (Online)

DOI:https://doi.org/10.1107/S1399004714025061· OSTI ID:1229000

Stauber, M; Jakoncic, J; Berger, J; Karp, J; Axelbaum, A; Sastow, D; Buldyrev, S; Hrnjez, B; Asherie, J

Cite

Export

Save

Research Organization:: Brookhaven National Lab. (BNL), Upton, NY (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

DOE Contract Number:: SC00112704

OSTI ID:: 1229000

Report Number(s):: BNL-111075-2015-JA

Journal Information:: Acta Crystallographica. Section D: Biological Crystallography (Online), Vol. D71, Issue 3; ISSN 1399-0047

Publisher:: International Union of Crystallography

Country of Publication:: United States

Language:: English

References (81)

Resolution of conglomerates by stereoselective habit modifications Addadi, L.; Berkovitch-Yellin, Z.; Domb, N. Nature, Vol. 296, Issue 5852 https://doi.org/10.1038/296021a0	journal	March 1982
Mechanistic Principles in Chiral Separations Using Liquid Chromatography and Capillary Electrophoresis Ali, I.; Kumerer, K.; Aboul-Enein, H. Y. Chromatographia, Vol. 63, Issue 7-8 https://doi.org/10.1365/s10337-006-0762-5	journal	April 2006
The Cambridge Structural Database: a quarter of a million crystal structures and rising Allen, Frank H. Acta Crystallographica Section B Structural Science, Vol. 58, Issue 3 https://doi.org/10.1107/S0108768102003890	journal	May 2002
A Hybrid Mechanism in Chiral Discrimination Induced by Crystallization of Supramolecular Compounds Amharar, Youness; Grandeury, Arnaud; Sanselme, Morgane The Journal of Physical Chemistry B, Vol. 116, Issue 20 https://doi.org/10.1021/jp301708v	journal	May 2012
An overview on 2-methyl-2,4-pentanediol in crystallization and in crystals of biological macromolecules Anand, Kanchan; Pal, Debnath; Hilgenfeld, Rolf Acta Crystallographica Section D Biological Crystallography, Vol. 58, Issue 10 https://doi.org/10.1107/S0907444902014610	journal	September 2002
Solubility of Thaumatin Asherie, Neer; Ginsberg, Charles; Blass, Samuel Crystal Growth & Design, Vol. 8, Issue 6 https://doi.org/10.1021/cg800276r	journal	June 2008
Effects of Protein Purity and Precipitant Stereochemistry on the Crystallization of Thaumatin ^† Asherie, Neer; Ginsberg, Charles; Greenbaum, Arieh Crystal Growth & Design, Vol. 8, Issue 12 https://doi.org/10.1021/cg800616q	journal	December 2008
Tartrate Chirality Determines Thaumatin Crystal Habit Asherie, Neer; Jakoncic, Jean; Ginsberg, Charles Crystal Growth & Design, Vol. 9, Issue 9 https://doi.org/10.1021/cg900465h	journal	September 2009
Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. I. Dependence on pH at 25° Aune, Kirk C.; Tanford, Charles Biochemistry, Vol. 8, Issue 11 https://doi.org/10.1021/bi00839a052	journal	November 1969
The Protein Data Bank Berman, H. M. Nucleic Acids Research, Vol. 28, Issue 1 https://doi.org/10.1093/nar/28.1.235	journal	January 2000
The origin of biological homochirality Blackmond, Donna G. Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 366, Issue 1580 https://doi.org/10.1098/rstb.2011.0130	journal	October 2011
Stereoselectivity in the Salt-Cocrystal Products formed by Phenylglycinol or Phenylglycine with their Respective Sodium or Hydrochloride Salts: STEREOSELECTIVITY IN THE SALT-COCRYSTAL PRODUCTS FORMED BY PHENYLGLYCINOL OR PHENYLGLYCINE Brittain, Harry G. Chirality, Vol. 25, Issue 1 https://doi.org/10.1002/chir.22103	journal	September 2012
The Significance of Chirality in Drug Design and Development H. Brooks, W.; C. Guida, W.; G. Daniel, K. Current Topics in Medicinal Chemistry, Vol. 11, Issue 7 https://doi.org/10.2174/156802611795165098	journal	April 2011
New software for searching the Cambridge Structural Database and visualizing crystal structures Bruno, Ian J.; Cole, Jason C.; Edgington, Paul R. Acta Crystallographica Section B Structural Science, Vol. 58, Issue 3 https://doi.org/10.1107/S0108768102003324	journal	May 2002
Cryoprotection properties of salts of organic acids: a case study for a tetragonal crystal of HEW lysozyme Bujacz, Grzegorz; Wrzesniewska, Blanka; Bujacz, Anna Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 7 https://doi.org/10.1107/S0907444910015416	journal	June 2010
Isothermal-isobaric molecular dynamics using stochastic velocity rescaling Bussi, Giovanni; Zykova-Timan, Tatyana; Parrinello, Michele The Journal of Chemical Physics, Vol. 130, Issue 7 https://doi.org/10.1063/1.3073889	journal	February 2009
Practical Physics Behind Growing Crystals of Biological Macromolecules Candoni, Nadine; Grossier, Romain; Hammadi, Zoubida Protein & Peptide Letters, Vol. 19, Issue 7 https://doi.org/10.2174/092986612800793136	journal	May 2012
Packing bridges in protein crystal structures Carugo, Oliviero; Djinović-Carugo, Kristina Journal of Applied Crystallography, Vol. 47, Issue 1 https://doi.org/10.1107/S160057671302880X	journal	December 2013
Using Graphs to Represent Crystallization Conditions Chan, Michelle; Fazio, Vincent J.; Newman, Janet Crystal Growth & Design, Vol. 13, Issue 3 https://doi.org/10.1021/cg301755a	journal	February 2013
Tackling the bottleneck of protein crystallization in the post-genomic era Chayen, Naomi E. Trends in Biotechnology, Vol. 20, Issue 3 https://doi.org/10.1016/S0167-7799(02)01916-9	journal	March 2002
Turning protein crystallisation from an art into a science Chayen, Naomi E. Current Opinion in Structural Biology, Vol. 14, Issue 5 https://doi.org/10.1016/j.sbi.2004.08.002	journal	October 2004
Is lysozyme really the ideal model protein? Chayen, Naomi E.; Saridakis, Emmanuel Journal of Crystal Growth, Vol. 232, Issue 1-4 https://doi.org/10.1016/S0022-0248(01)01203-9	journal	November 2001
Protein crystallization: from purified protein to diffraction-quality crystal Chayen, Naomi E.; Saridakis, Emmanuel Nature Methods, Vol. 5, Issue 2 https://doi.org/10.1038/nmeth.f.203	journal	January 2008
Porous silicon: an effective nucleation-inducing material for protein crystallization 1 1Edited by R. Huber Chayen, N. E.; Saridakis, E.; El-Bahar, R. Journal of Molecular Biology, Vol. 312, Issue 4 https://doi.org/10.1006/jmbi.2001.4995	journal	September 2001
Efficient diffuse function-augmented basis sets for anion calculations. III. The 3-21+G basis set for first-row elements, Li-F Clark, Timothy; Chandrasekhar, Jayaraman; Spitznagel, G�nther W. Journal of Computational Chemistry, Vol. 4, Issue 3 https://doi.org/10.1002/jcc.540040303	journal	October 1983
Step velocity in tetragonal lysozyme growth as a function of impurity concentration and mass transport conditions Dold, P.; Ono, E.; Tsukamoto, K. Journal of Crystal Growth, Vol. 293, Issue 1 https://doi.org/10.1016/j.jcrysgro.2006.04.116	journal	July 2006
Comparative Effects of Salt, Organic, and Polymer Precipitants on Protein Phase Behavior and Implications for Vapor Diffusion Dumetz, André C.; Chockla, Aaron M.; Kaler, Eric W. Crystal Growth & Design, Vol. 9, Issue 2 https://doi.org/10.1021/cg700956b	journal	February 2009
Efficient Resolution of Enantiomers by Coupling Preferential Crystallization and Dissolution. Part 2: A Parametric Simulation Study to Identify Suitable Process Conditions Eicke, Matthias J.; Levilain, Guillaume; Seidel-Morgenstern, Andreas Crystal Growth & Design, Vol. 13, Issue 4 https://doi.org/10.1021/cg3018503	journal	March 2013
Features and development of Coot Emsley, P.; Lohkamp, B.; Scott, W. G. Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4 https://doi.org/10.1107/S0907444910007493	journal	March 2010
A smooth particle mesh Ewald method Essmann, Ulrich; Perera, Lalith; Berkowitz, Max L. The Journal of Chemical Physics, Vol. 103, Issue 19 https://doi.org/10.1063/1.470117	journal	November 1995
Effects of purification on the crystallization of lysozyme Ewing, Felecia L.; Forsythe, Elizabeth L.; van der Woerd, Mark Journal of Crystal Growth, Vol. 160, Issue 3-4 https://doi.org/10.1016/0022-0248(95)00933-7	journal	March 1996
Improved isolation and crystallization of photosystem I for structural analysis Fromme, Petra; Witt, Horst Tobias Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1365, Issue 1-2 https://doi.org/10.1016/S0005-2728(98)00059-0	journal	June 1998
The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods Gabanyi, Margaret J.; Adams, Paul D.; Arnold, Konstantin Journal of Structural and Functional Genomics, Vol. 12, Issue 2 https://doi.org/10.1007/s10969-011-9106-2	journal	April 2011
The discovery of biological enantioselectivity: Louis Pasteur and the fermentation of tartaric acid, 1857—A review and analysis 150 yr later Gal, Joseph Chirality, Vol. 20, Issue 1 https://doi.org/10.1002/chir.20494	journal	January 2007
Louis Pasteur, language, and molecular chirality. I. Background and Dissymmetry Gal, Joseph Chirality, Vol. 23, Issue 1 https://doi.org/10.1002/chir.20866	journal	December 2010
Controlled Crystallization of Macromolecules using Patterned Substrates in a Sandwiched Plate Geometry Ghatak, Anindita Sengupta; Ghatak, Animangsu Industrial & Engineering Chemistry Research, Vol. 50, Issue 23 https://doi.org/10.1021/ie102596c	journal	December 2011
Investigation of a Chiral Additive Used in Preferential Crystallization Gou, Linzhu; Lorenz, Heike; Seidel-Morgenstern, Andreas Crystal Growth & Design, Vol. 12, Issue 11 https://doi.org/10.1021/cg300042q	journal	October 2012
Recent progresses in protein-based chiral stationary phases for enantioseparations in liquid chromatography☆ Haginaka, J. Journal of Chromatography B, Vol. 875, Issue 1 https://doi.org/10.1016/j.jchromb.2008.05.022	journal	November 2008
The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation Helliwell, John R.; Tanley, Simon William Maurice Acta Crystallographica Section D Biological Crystallography, Vol. 69, Issue 1 https://doi.org/10.1107/S090744491204423X	journal	December 2012
GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation Hess, Berk; Kutzner, Carsten; van der Spoel, David Journal of Chemical Theory and Computation, Vol. 4, Issue 3 https://doi.org/10.1021/ct700301q	journal	February 2008
On the propagation of errors Jaskolski, Mariusz Acta Crystallographica Section D Biological Crystallography, Vol. 69, Issue 10 https://doi.org/10.1107/S090744491301528X	journal	September 2013
Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids Jorgensen, William L.; Maxwell, David S.; Tirado-Rives, Julian Journal of the American Chemical Society, Vol. 118, Issue 45 https://doi.org/10.1021/ja9621760	journal	January 1996
The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin Jorgensen, William L.; Tirado-Rives, Julian Journal of the American Chemical Society, Vol. 110, Issue 6 https://doi.org/10.1021/ja00214a001	journal	March 1988
The effect of protein impurities on lysozyme crystal growth Judge, Russell A.; Forsythe, Elizabeth L.; Pusey, Marc L. Biotechnology and Bioengineering, Vol. 59, Issue 6 https://doi.org/10.1002/(SICI)1097-0290(19980920)59:6<776::AID-BIT14>3.0.CO;2-3	journal	September 1998
The Effect of Temperature and Solution pH on the Nucleation of Tetragonal Lysozyme Crystals Judge, Russell A.; Jacobs, Randolph S.; Frazier, Tyralynn Biophysical Journal, Vol. 77, Issue 3 https://doi.org/10.1016/S0006-3495(99)77006-2	journal	September 1999
On vital aid: the why, what and how of validation Kleywegt, Gerard J. Acta Crystallographica Section D Biological Crystallography, Vol. 65, Issue 2 https://doi.org/10.1107/S090744490900081X	journal	January 2009
The Uppsala Electron-Density Server Kleywegt, Gerard J.; Harris, Mark R.; Zou, Jin-yu Acta Crystallographica Section D Biological Crystallography, Vol. 60, Issue 12 https://doi.org/10.1107/S0907444904013253	journal	November 2004
Chiral recognition by enantioselective liquid chromatography: Mechanisms and modern chiral stationary phases Lämmerhofer, Michael Journal of Chromatography A, Vol. 1217, Issue 6 https://doi.org/10.1016/j.chroma.2009.10.022	journal	February 2010
PROCHECK: a program to check the stereochemical quality of protein structures Laskowski, R. A.; MacArthur, M. W.; Moss, D. S. Journal of Applied Crystallography, Vol. 26, Issue 2 https://doi.org/10.1107/S0021889892009944	journal	April 1993
Efficient Resolution of Enantiomers by Coupling Preferential Crystallization and Dissolution. Part 1: Experimental Proof of Principle Levilain, Guillaume; Eicke, Matthias J.; Seidel-Morgenstern, Andreas Crystal Growth & Design, Vol. 12, Issue 11 https://doi.org/10.1021/cg3009943	journal	October 2012
Shape evolution and thermal stability of lysozyme crystals: effect of pH and temperature Liang, Miao; Jin, Fengmin; Liu, Rui Bioprocess and Biosystems Engineering, Vol. 36, Issue 1 https://doi.org/10.1007/s00449-012-0764-7	journal	June 2012
The influence of impurities on protein crystallization; the case of lysozyme Lorber, Bernard; Skouri, Mohammed; Munch, Jean-Pierre Journal of Crystal Growth, Vol. 128, Issue 1-4 https://doi.org/10.1016/S0022-0248(07)80124-2	journal	March 1993
Processes To Separate Enantiomers Lorenz, Heike; Seidel-Morgenstern, Andreas Angewandte Chemie International Edition, Vol. 53, Issue 5 https://doi.org/10.1002/anie.201302823	journal	January 2014
A simple technique for consistently obtaining large single crystals of hen egg-white lysozyme in a concentration gradient of NiCl ₂ Magay, Elena; Yoon, Tae-Sung Journal of Applied Crystallography, Vol. 44, Issue 1 https://doi.org/10.1107/S0021889810044936	journal	December 2010
A scheme estimating the energy of intramolecular hydrogen bonds in diols Mandado, Marcos; Mosquera, Ricardo A.; Alsenoy, Christian Van Tetrahedron, Vol. 62, Issue 17 https://doi.org/10.1016/j.tet.2006.01.085	journal	April 2006
The Role of Small Molecule Additives and Chemical Modification in Protein Crystallization McPherson, A.; Nguyen, C.; Cudney, R. Crystal Growth & Design, Vol. 11, Issue 5 https://doi.org/10.1021/cg101308r	journal	May 2011
Protecting role of cosolvents in protein denaturation by SDS: a structural study Michaux, Catherine; Pouyez, Jenny; Wouters, Johan BMC Structural Biology, Vol. 8, Issue 1 https://doi.org/10.1186/1472-6807-8-29	journal	January 2008
A Critical Analysis on the Rotation Barriers in Butane Mo, Yirong The Journal of Organic Chemistry, Vol. 75, Issue 8 https://doi.org/10.1021/jo1001164	journal	April 2010
Note on an Approximation Treatment for Many-Electron Systems Møller, Chr.; Plesset, M. S. Physical Review, Vol. 46, Issue 7 https://doi.org/10.1103/PhysRev.46.618	journal	October 1934
REFMAC 5 for the refinement of macromolecular crystal structures Murshudov, Garib N.; Skubák, Pavol; Lebedev, Andrey A. Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4 https://doi.org/10.1107/S0907444911001314	journal	March 2011
A Novel Transition-state Analogue for Lysozyme, 4- O -β-Tri- N -acetylchitotriosyl Moranoline, Provided Evidence Supporting the Covalent Glycosyl-enzyme Intermediate Ogata, Makoto; Umemoto, Naoyuki; Ohnuma, Takayuki Journal of Biological Chemistry, Vol. 288, Issue 9 https://doi.org/10.1074/jbc.M112.439281	journal	January 2013
[20] Processing of X-ray diffraction data collected in oscillation mode Otwinowski, Zbyszek; Minor, Wladek Macromolecular Crystallography Part A, 307-326 https://doi.org/10.1016/S0076-6879(97)76066-X	book	January 1997
Pre-assembled clusters distort crystal nucleation kinetics in supersaturated lysozyme solutions Parmar, Avanish S.; Gottschall, Paul E.; Muschol, Martin Biophysical Chemistry, Vol. 129, Issue 2-3 https://doi.org/10.1016/j.bpc.2007.06.002	journal	September 2007
X-ray Structure of Snow Flea Antifreeze Protein Determined by Racemic Crystallization of Synthetic Protein Enantiomers Pentelute, Brad L.; Gates, Zachary P.; Tereshko, Valentina Journal of the American Chemical Society, Vol. 130, Issue 30 https://doi.org/10.1021/ja8013538	journal	July 2008
Spontaneous resolution under supramolecular control Pérez-García, Lluïsa; Amabilino, David B. Chem. Soc. Rev., Vol. 31, Issue 6 https://doi.org/10.1039/B201099M	journal	January 2002
Life in the fast lane for protein crystallization and X-ray crystallography Pusey, M.; Liu, Z.; Tempel, W. Progress in Biophysics and Molecular Biology, Vol. 88, Issue 3 https://doi.org/10.1016/j.pbiomolbio.2004.07.011	journal	July 2005
Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes Ryckaert, Jean-Paul; Ciccotti, Giovanni; Berendsen, Herman J. C. Journal of Computational Physics, Vol. 23, Issue 3 https://doi.org/10.1016/0021-9991(77)90098-5	journal	March 1977
High-level theoretical study of the conformational equilibrium of n -pentane Salam, A.; Deleuze, M. S. The Journal of Chemical Physics, Vol. 116, Issue 4 https://doi.org/10.1063/1.1429243	journal	January 2002
Structure of tetragonal hen egg-white lysozyme at 0.94 Å from crystals grown by the counter-diffusion method Sauter, Claude; Otálora, Fermin; Gavira, José-Antonio Acta Crystallographica Section D Biological Crystallography, Vol. 57, Issue 8 https://doi.org/10.1107/S0907444901008873	journal	July 2001
Single-wavelength phasing strategy for quasi-racemic protein crystal diffraction data Sawaya, Michael R.; Pentelute, Brad L.; Kent, Stephen B. H. Acta Crystallographica Section D Biological Crystallography, Vol. 68, Issue 1 https://doi.org/10.1107/S0907444911049985	journal	December 2011
Continuous surface charge polarizable continuum models of solvation. I. General formalism Scalmani, Giovanni; Frisch, Michael J. The Journal of Chemical Physics, Vol. 132, Issue 11 https://doi.org/10.1063/1.3359469	journal	March 2010
Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein Tanley, Simon W. M.; Schreurs, Antoine M. M.; Kroon-Batenburg, Loes M. J. Acta Crystallographica Section D Biological Crystallography, Vol. 68, Issue 5 https://doi.org/10.1107/S0907444912006907	journal	April 2012
Heterogeneity Determination and Purification of Commercial Hen Egg-White Lysozyme Thomas, B. R.; Vekilov, P. G.; Rosenberger, F. Acta Crystallographica Section D Biological Crystallography, Vol. 52, Issue 4 https://doi.org/10.1107/S090744499600279X	journal	July 1996
Quantum Mechanical Continuum Solvation Models Tomasi, Jacopo; Mennucci, Benedetta; Cammi, Roberto Chemical Reviews, Vol. 105, Issue 8 https://doi.org/10.1021/cr9904009	journal	August 2005
Effect of surface chemistry of novel templates on crystallization of proteins Tsekova, Daniela S.; Williams, Daryl R.; Heng, Jerry Y. Y. Chemical Engineering Science, Vol. 77 https://doi.org/10.1016/j.ces.2012.01.049	journal	July 2012
Crystal Growth of Lysozyme Controlled by Laser Trapping Tu, Jing-Ru; Miura, Atsushi; Yuyama, Ken-ichi Crystal Growth & Design, Vol. 14, Issue 1 https://doi.org/10.1021/cg401065h	journal	November 2013
Molecular replacement with MOLREP Vagin, Alexei; Teplyakov, Alexei Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 1 https://doi.org/10.1107/S0907444909042589	journal	December 2009
Crystallization, structure solution and refinement of hen egg-white lysozyme at pH 8.0 in the presence of MPD Weiss, Manfred S.; Palm, Gottfried J.; Hilgenfeld, Rolf Acta Crystallographica Section D Biological Crystallography, Vol. 56, Issue 8 https://doi.org/10.1107/S0907444900006685	journal	August 2000
Applications of the second virial coefficient: protein crystallization and solubility Wilson, William W.; DeLucas, Lawrence J. Acta Crystallographica Section F Structural Biology Communications, Vol. 70, Issue 5 https://doi.org/10.1107/S2053230X1400867X	journal	April 2014
Overview of the CCP 4 suite and current developments Winn, Martyn D.; Ballard, Charles C.; Cowtan, Kevin D. Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4 https://doi.org/10.1107/S0907444910045749	journal	March 2011
Racemic Protein Crystallography Yeates, Todd O.; Kent, Stephen B. H. Annual Review of Biophysics, Vol. 41, Issue 1 https://doi.org/10.1146/annurev-biophys-050511-102333	journal	June 2012

Cited By (1)

An Analysis on Commercial Screening Kits and Chemical Components in Biomacromolecular Crystallization Screening Qin, Wei; Xie, Si-Xiao; Zhang, Jie Crystal Research and Technology, Vol. 54, Issue 9 https://doi.org/10.1002/crat.201900076	journal	August 2019

Similar Records

Crystallization of lysozyme with (R)-, (S)- and (RS)-2-methyl-2,4-pentanediol

Journal Article · Sun Mar 01 00:00:00 EST 2015 · Acta Crystallographica. Section D: Biological Crystallography (Online) · OSTI ID:1229000

Stauber, Mark; Jakoncic, Jean; Berger, Jacob; +6 more

Crystallization of lysozyme with (R)-, (S)- and (RS)-2-methyl-2, 4-pentanediol

Journal Article · Sun Mar 01 00:00:00 EST 2015 · Acta Crystallographica. Section D: Biological Crystallography · OSTI ID:1229000

Stauber, Mark; Jakoncic, Jean; Berger, Jacob; +6 more

Atomic resolution experimental phase information reveals extensive disorder and bound 2-methyl-2,4-pentanediol in Ca ²⁺ -calmodulin

Journal Article · Fri Jan 01 00:00:00 EST 2016 · Acta Crystallographica. Section D. Structural Biology · OSTI ID:1229000

Lin, Jiusheng; van den Bedem, Henry; Brunger, Axel T.; +1 more

Title: Crystallization of Lysozyme with (R)-, (S)- and (RS)-2-methyl-2,4-pentanediol

Citation Formats

References (81)

Cited By (1)

Similar Records

Related Subjects