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Title: The life science X-ray scattering beamline at NSLS-II

Journal Article · · AIP Conference Proceedings
DOI:https://doi.org/10.1063/1.4952872· OSTI ID:1228834
 [1];  [1];  [1];  [1];  [1];  [1];  [2];  [1]
  1. Brookhaven National Lab. (BNL), Upton, NY (United States)
  2. Brookhaven National Lab. (BNL), Upton, NY (United States); Institut fur Werkstoffforschung, Hamburg (Germany)

We report the current development status of the High Brightness X-ray Scattering for Life Sciences (or Life Science X-ray Scattering, LiX) beamline at the NSLS-II facility of Brookhaven National Laboratory. This instrument will operate in the x-ray energy range of 2.1-18 keV, provide variable beam sizes from 1 micron to ~0.5 mm, and support user experiments in three scientific areas: (1) high-throughput solution scattering, in-line size exclusion chromatography and flow mixers-based time-resolved solution scattering of biological macro-molecules, (2) diffraction from single- and multi-layered lipid membranes, and (3) scattering-based scanning probe imaging of biological tissues. In order to satisfy the beam stability required for these experiments and to switch rapidly between different types of experiments, we have adopted a secondary source with refractive lenses for secondary focusing, a detector system consisting of three Pilatus detectors, and specialized experimental modules that can be quickly exchanged and each dedicated to a defined set of experiments. The construction of this beamline is on schedule for completion in September 2015. User experiments are expected to start in Spring 2016.

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
SC00112704
OSTI ID:
1228834
Report Number(s):
BNL-108470-2015-JA; R&D Project: LS001
Journal Information:
AIP Conference Proceedings, Vol. 1741; Conference: Synchrotron Radiation Instrumentation (SRI 2015), New York, NY (United States, 6-10 Jul 2015; ISSN 0094-243X
Publisher:
AIPCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 19 works
Citation information provided by
Web of Science

References (3)

Enhanced laser shutter using a hard disk drive rotary voice-coil actuator journal February 2007
P03, the microfocus and nanofocus X-ray scattering (MiNaXS) beamline of the PETRA III storage ring: the microfocus endstation journal May 2012
X-ray diffraction from rectangular slits journal June 2002

Cited By (1)

Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses journal March 2020

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