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Title: Biocatalysts with enhanced inhibitor tolerance

Patent ·
OSTI ID:1228373
; ; ; ;

Disclosed herein are biocatalysts for the production of biofuels, including microorganisms that contain genetic modifications conferring tolerance to growth and fermentation inhibitors found in many cellulosic feedstocks. Methods of converting cellulose-containing materials to fuels and chemicals, as well as methods of fermenting sugars to fuels and chemicals, using these biocatalysts are also disclosed.

Research Organization:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC36-08GO28308
Assignee:
Alliance for Sustainable Energy, LLC
Patent Number(s):
9,206,445
Application Number:
14/265,039
OSTI ID:
1228373
Resource Relation:
Patent File Date: 2014 Apr 29
Country of Publication:
United States
Language:
English

References (13)

Method for analyzing and synthesizing functional polypeptide sequences for assembly into enhanced or multi-functional proteins patent August 1990
Recombinant zymomonas for pentose fermentation patent May 1996
Single zymomonas mobilis strain for xylose and arabinose fermentation patent December 1998
Recombinant Zymomonas mobilis with improved xylose utilization patent May 2003
Zymomonas pentose-sugar fermenting strains and uses thereof patent May 2007
Stable zymomonas mobilis xylose and arabinose fermenting strains patent April 2008
Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate patent September 2010
Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate patent March 2011
Microorganisms Having Enhanced Tolerance To Inhibitors and Stress patent-application December 2010
Use of the tac promoter and lacIq for the controlled expression of Zymomonas mobilis fermentative genes in Escherichia coli and Zymomonas mobilis. journal November 1992
Pretreatment of Lignocellulosic Materials for Efficient Bioethanol Production book January 2007
Location of a region of the muscarinic acetylcholine receptor involved in selective effector coupling journal December 1988
Characterization of multiple promoters and transcript stability in the sacB–sacC gene cluster in Zymomonas mobilis journal May 2009

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