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Title: Digital microfluidic platform for radiochemistry

Patent ·
OSTI ID:1226827
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Disclosed herein are methods of performing microchemical reactions and electro-wetting-on-dielectric devices (EWOD devices) for use in performing those reactions. These devices and method are particularly suited for preparing radiochemical compounds, particularly compounds containing .sup.18F.

Research Organization:
Univ. of California, Oakland, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
SC0005056
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
9,193,640
Application Number:
14/643,151
OSTI ID:
1226827
Resource Relation:
Patent File Date: 2015 Mar 10
Country of Publication:
United States
Language:
English

References (8)

Actuators for microfluidics without moving parts patent May 2003
Rapid Multi-Material Sample Input System patent-application November 2003
Method for Multi-Batch Production of FDG patent-application February 2004
Droplet-Based Washing patent-application October 2007
Fully-Automated Microfluidic System for the Synthesis of Radiolabeled Biomarkers for Positron Emission Tomography patent-application September 2008
Microreactors for radiopharmaceutical synthesis journal January 2009
Positron Emission Tomography (PET) and Microfluidic Devices: A Breakthrough on the Microscale? journal March 2007
Multistep Synthesis of a Radiolabeled Imaging Probe Using Integrated Microfluidics journal December 2005

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38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY