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Title: Genome Sequencing of 18 Francisella Strains To Aid in Assay Development and Testing

Journal Article · · Genome Announcements
ORCiD logo [1];  [1];  [1];  [2];  [3];  [4];  [5];  [3];  [1];  [1];  [1];  [2];  [4];  [5];  [5];  [4];  [3];  [1];  [2];  [1]
  1. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
  2. United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland (United States). Diagnostic Systems Division
  3. Naval Medical Research Center (NMRC)-Frederick, Fort Detrick, Maryland (United States); Henry M. Jackson Foundation, Bethesda, Maryland (United States)
  4. United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland (United States)
  5. United States Army Edgewood Chemical Biological Center (ECBC), Aberdeen, Maryland (United States)

Francisella tularensis is a highly infectious bacterium that has the potential of causing high fatality rates if infections are untreated. To aid in the development of rapid and accurate detection assays, we have sequenced and annotated the genomes of 18 F. tularensis and Francisella philomiragia strains.

Research Organization:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE
Grant/Contract Number:
AC52-06NA25396
OSTI ID:
1221144
Report Number(s):
LA-UR-14-29607
Journal Information:
Genome Announcements, Vol. 3, Issue 2; ISSN 2169-8287
Publisher:
American Society for MicrobiologyCopyright Statement
Country of Publication:
United States
Language:
English

References (11)

An Ergatis-based prokaryotic genome annotation web server journal March 2010
The Infectious Dose of Francisella Tularensis (Tularemia) journal December 2005
Analysis of 16S Ribosomal DNA Sequences of Francisella Strains and Utilization for Determination of the Phylogeny of the Genus and for Identification of Strains by PCR journal January 1994
Genome Project Standards in a New Era of Sequencing journal October 2009
ALLPATHS: De novo assembly of whole-genome shotgun microreads journal February 2008
Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data journal May 2013
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs journal February 2008
Base-Calling of Automated Sequencer Traces Using Phred.  I. Accuracy Assessment journal March 1998
Public Health Assessment of Potential Biological Terrorism Agents journal February 2002
Consed: A Graphical Tool for Sequence Finishing journal March 1998
Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities journal March 1998

Cited By (3)

Whole-Genome Relationships among Francisella Bacteria of Diverse Origins Define New Species and Provide Specific Regions for Detection journal November 2016
Shared features of cryptic plasmids from environmental and pathogenic Francisella species journal August 2017
Development of a recombinase polymerase amplification assay for rapid detection of Francisella noatunensis subsp. orientalis journal February 2018