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Title: Dendrimers and methods of preparing same through proportionate branching

Patent ·
OSTI ID:1215551

The present invention provides for monodispersed dendrimers having a core, branches and periphery ends, wherein the number of branches increases exponentially from the core to the periphery end and the length of the branches increases exponentially from the periphery end to the core, thereby providing for attachment of chemical species at the periphery ends without exhibiting steric hindrance.

Research Organization:
University of Maryland Baltimore, Baltimore, MD (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-08CH11527
Assignee:
University of Maryland, Baltimore (Baltimore, MD)
Patent Number(s):
9,133,114
Application Number:
13/752,482
OSTI ID:
1215551
Resource Relation:
Patent File Date: 2013 Jan 29
Country of Publication:
United States
Language:
English

References (27)

Branced polyoxaalkyl macromolecules patent July 1998
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine journal April 2010
Synthesis and relaxometry of high-generation (G = 5, 7, 9, and 10) PAMAM dendrimer-DOTA-gadolinium chelates journal February 1999
Fluorinated dendrimers journal August 2003
Extraction of a hydrophilic compound from water into liquid CO2 using dendritic surfactants journal September 1997
Self-assembly of pH-responsive fluorinated dendrimer-based particulates for drug delivery and noninvasive imaging journal August 2009
DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering journal January 2009
Functional polymers and dendrimers: reactivity, molecular architecture, and interfacial energy journal March 1994
Convergent Dendrons and Dendrimers:  from Synthesis to Applications journal December 2001
The Synthesis of a Geminally Perfluoro- tert -butylated β-Amino Acid and its Protected Forms as a Potential Pharmacokinetic Modulator and Reporter for Peptide-Based Pharmaceuticals journal February 2007
The design and synthesis of highly branched and spherically symmetric fluorinated oils and amphiles journal May 2007
Symmetry-Guided Design and Fluorous Synthesis of a Stable and Rapidly Excreted Imaging Tracer for 19F MRI journal June 2009
Fluorous Mixture Synthesis of Asymmetric Dendrimers journal March 2010
Homogeneous catalysts based on silane dendrimers functionalized with arylnickel(II) complexes journal December 1994
PRIMUS: a Windows PC-based system for small-angle scattering data analysis journal September 2003
Automated matching of high- and low-resolution structural models journal February 2001
Greener fluorous chemistry: Convenient preparation of new types of ‘CF3-rich’ secondary alkyl mesylates and their use for the synthesis of azides, amines, imidazoles and imidazolium salts journal December 2010
Dendrimers Derived from 1 → 3 Branching Motifs journal October 2010
Controlling polymer shape through the self-assembly of dendritic side-groups journal January 1998
Self-organization of supramolecular helical dendrimers into complex electronic materials journal September 2002
Dendrimers in biomedical applications—reflections on the field journal December 2005
Determination of the regularization parameter in indirect-transform methods using perceptual criteria journal August 1992
Restoring Low Resolution Structure of Biological Macromolecules from Solution Scattering Using Simulated Annealing journal June 1999
Novel generation ponytails in fluorous chemistry: Syntheses of primary, secondary, and tertiary (nonafluoro-tert-butyloxy)ethyl amines journal November 2006
In quest of a systematic framework for unifying and defining nanoscience journal May 2009
Uniqueness of ab initio shape determination in small-angle scattering journal April 2003
Rapid Construction of Large-size Phenylacetylene Dendrimers up to 12.5 Nanometers in Molecular Diameter journal September 1993

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