Sensitive ion detection device and method for analysis of compounds as vapors in gases

Denton, M. Bonner; Sperline, Roger P.

Title: Sensitive ion detection device and method for analysis of compounds as vapors in gases

Patent · Tue Sep 15 00:00:00 EDT 2015

OSTI ID:1214596

Denton, M. Bonner; Sperline, Roger P.

An ion mobility spectrometer (IMS) for the detection of trace gaseous molecular compounds dissolved or suspended in a carrier gas, particularly in ambient air, without preconcentration or the trapping of analyte particles. The IMS of the invention comprises an ionization volume of greater than 5 cm.sup.3 and preferably greater than 100 cm.sup.3. The larger size ionizers of this invention enable analysis of trace (<1 ppb) of sample compounds in the gas phase. To facilitate efficient ion motion through the large volume ionization and reaction regions of the IMS, an electric field gradient can be provided in the ionization region or in both the ionization and reaction regions. The systems can be implemented with radioactive ionization sources, corona discharge ion sources or ions can be formed by photoionization. In specific embodiments, particularly when the sample gas is ambient air, the sample gas is heater prior to entry into the instrument, the instrument is run at temperatures above ambient, and the instrument can be heated by contact with heated sample gas exiting the instrument.

View Patent

Cite

Export

Save

Research Organization:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: The Arizona Board of Regents on behalf of the University of Arizona (Phoenix, AZ)

Patent Number(s):: 9,134,272

Application Number:: 14/046,447

OSTI ID:: 1214596

Resource Relation:: Patent File Date: 2013 Oct 04

Country of Publication:: United States

Language:: English

References (29)

Reliable dynamoelectric machine condition monitor Fort, Emil M. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4121458 US Patent Document 4,121,458	patent	October 1978
Magnetic fixture assembly Cory, Michael; Dean, Donald W. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4777463 US Patent Document 4,777,463	patent	October 1988
Ion source for quadrupole mass spectrometer Devant, Gerard; Evrard, Robert; Maulat, Olivier https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5153432 US Patent Document 5,153,432	patent	October 1992
High pressure selected ion chemical ionization interface for connecting a sample source to an analysis device Eisele, Fred L.; Berresheim, Harald https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5175431 US Patent Document 5,175,431	patent	December 1992
Ion mobility spectrometers Jenkins, Anthony https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5200614 US Patent Document 5,200,614	patent	April 1993
Ion source and sample introduction method and apparatus using two stage ionization for producing sample gas ions Eisele, Fred L.; Berresheim, Harald https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5218203 US Patent Document 5,218,203	patent	June 1993
Selective detection with high speed gas chromatography Rounbehler, David P.; Hainsworth, Eugenie; Lieb, David P. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5310681 US Patent Document 5,310,681	patent	May 1994
Ion gun and mass spectrometer employing the same Mullock, Stephen J. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5563410 US Patent Document 5,563,410	patent	October 1996
Explosive detection screening system Corrigan, Colin; Haley, Lawrence V. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5585575 US Patent Document 5,585,575	patent	December 1996
Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas Loboda, Alexandre https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6630662 US Patent Document 6,630,662	patent	October 2003
Mass spectrometer Giles, Kevin; Hoyes, John Brian; Pringle, Steve https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6791078 US Patent Document 6,791,078	patent	September 2004
Mass spectrometer Hoyes, John Brian https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6906319 US Patent Document 6,906,319	patent	June 2005
Mass spectrometer Bateman, Robert Harold; Hoyes, John Brian; Langridge, James Ian https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6992283 US Patent Document 6,992,283	patent	January 2006
Use of conductive glass tubes to create electric fields in ion mobility spectrometers Laprade, Bruce https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7081618 US Patent Document 7,081,618	patent	July 2006
Remote reagent chemical ionization source Sheehan, Edward William; Willoughby, Ross C. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7095019 US Patent Document 7,095,019	patent	August 2006
Apparatus and method for adjustment of ion separation resolution in FAIMS Kapron, James T.; Guevremont, Roger https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7227132 US Patent Document 7,227,132	patent	June 2007
Ion detection device and method with compressing ion-beam shutter Sperline, Roger P. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7538320 US Patent Document 7,538,320	patent	May 2009
Remote reagent ion generator Karpetsky, Timothy P.; Berends, Jr., John C.; Sheehan, Edward William https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7569812 US Patent Document 7,569,812	patent	August 2009
Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices Miller, Raanan A.; Nazarov, Erkinjon G.; Wheeler, David https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7608818 US Patent Document 7,608,818	patent	October 2009
Sensitive ion detection device and method for analysis of compounds as vapors in gases Denton, M. Bonner; Sperline, Roger P. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8653449 US Patent Document 8,653,449	patent	February 2014
An analysis of the current in a point-to-plane corona discharge and the effect of a back-ionising layer on the plane Cross, J. A. Journal of Physics D: Applied Physics, Vol. 18, Issue 12 https://doi.org/10.1088/0022-3727/18/12/014	journal	December 1985
Ion mobility spectrometry Hill, Herbert H.; Siems, William F.; St. Louis, Robert H. Analytical Chemistry, Vol. 62, Issue 23 https://doi.org/10.1021/ac00222a001	journal	December 1990
Electrical characteristics of a corona discharge reactor of multipoint-to-plane geometry Jaworek, A.; Krupa, A. Czechoslovak Journal of Physics, Vol. 45, Issue 12 https://doi.org/10.1007/BF01691996	journal	December 1995
Current density distribution measurement of negative point-to-plane corona discharge Madani, M. R.; Miller, T. A. IEEE Transactions on Instrumentation and Measurement, Vol. 47, Issue 4 https://doi.org/10.1109/19.744641	journal	January 1998
Effects of interfacial interaction potential on the sublimation rates of TNT films on a silica surface examined by QCM and AFM techniques Mu, R.; Ueda, A.; Liu, Y. C. Surface Science, Vol. 530, Issue 1-2, p. L293-L296 https://doi.org/10.1016/S0039-6028(03)00380-7	journal	April 2003
Electrospray Ionization High-Resolution Ion Mobility Spectrometry−Mass Spectrometry Wu, Ching; Siems, William F.; Asbury, G. Reid Analytical Chemistry, Vol. 70, Issue 23 https://doi.org/10.1021/ac980414z	journal	December 1998
Ultrafast Differential Ion Mobility Spectrometry at Extreme Electric Fields in Multichannel Microchips Shvartsburg, Alexandre A.; Smith, Richard D.; Wilks, Ashley Analytical Chemistry, Vol. 81, Issue 15 https://doi.org/10.1021/ac900892u	journal	August 2009
Ultrafast Differential Ion Mobility Spectrometry at Extreme Electric Fields Coupled to Mass Spectrometry Shvartsburg, Alexandre A.; Tang, Keqi; Smith, Richard D. Analytical Chemistry, Vol. 81, Issue 19 https://doi.org/10.1021/ac901479e	journal	October 2009
Accelerated High-Resolution Differential Ion Mobility Separations Using Hydrogen Shvartsburg, Alexandre A.; Smith, Richard D. Analytical Chemistry, Vol. 83, Issue 23 https://doi.org/10.1021/ac202386w	journal	December 2011

Similar Records

Sensitive ion detection device and method for analysis of compounds as vapors in gases

Patent · Tue Feb 18 00:00:00 EST 2014 · OSTI ID:1214596

Denton, M. Bonner; Sperline, Roger P

Photoionization in air with ion mobility spectrometry using a hydrogen discharge lamp

Journal Article · Mon Sep 01 00:00:00 EDT 1986 · Anal. Chem.; (United States) · OSTI ID:1214596

Leasure, C S; Fleischer, M E; Anderson, G K; +1 more

Ion storage techniques and time-of-flight mass spectrometry in physical forensic science

Conference · Tue Jun 27 00:00:00 EDT 2000 · OSTI ID:1214596

Chambers, D M; Grace, L I

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY

Title: Sensitive ion detection device and method for analysis of compounds as vapors in gases

Citation Formats

References (29)

Similar Records

Related Subjects