Nanostructure-initiator mass spectrometry biometrics

Leclerc, Marion; Bowen, Benjamin; Northen, Trent

Title: Nanostructure-initiator mass spectrometry biometrics

Patent · Tue Sep 08 00:00:00 EDT 2015

OSTI ID:1214154

Leclerc, Marion; Bowen, Benjamin; Northen, Trent

Several embodiments described herein are drawn to methods of identifying an analyte on a subject's skin, methods of generating a fingerprint, methods of determining a physiological change in a subject, methods of diagnosing health status of a subject, and assay systems for detecting an analyte and generating a fingerprint, by nanostructure-initiator mass spectrometry (NIMS).

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 9,125,596

Application Number:: 13/631,687

OSTI ID:: 1214154

Resource Relation:: Patent File Date: 2012 Sep 28

Country of Publication:: United States

Language:: English

References (7)

Nanomanipulation coupled nanospray mass spectrometry (NMS) Verbeck, IV, Guido Fridolin https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8766177 US Patent Document 8,766,177	patent	July 2014
Nanostructure-Initiator Mass Spectrometry Northen, Trent; Siuzdak, Gary; Nordstrom, Anders https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20080128608 US Patent Document 11/852863; 20080128608	patent-application	June 2008
Detection of drugs and their metabolites in dusted latent fingermarks by mass spectrometry Rowell, Frederick; Hudson, Katherine; Seviour, John The Analyst, Vol. 134, Issue 4 https://doi.org/10.1039/B813957C	journal	January 2009
Direct detection of peptides and small proteins in fingermarks and determination of sex by MALDI mass spectrometry profiling Ferguson, Leesa Susanne; Wulfert, Florian; Wolstenholme, Rosalind The Analyst, Vol. 137, Issue 20 https://doi.org/10.1039/C2AN36074H	journal	January 2012
Clathrate nanostructures for mass spectrometry Northen, Trent R.; Yanes, Oscar; Northen, Michael T. Nature, Vol. 449, Issue 7165 https://doi.org/10.1038/nature06195	journal	October 2007
A nanostructure-initiator mass spectrometry-based enzyme activity assay Northen, T. R.; Lee, J.-C.; Hoang, L. Proceedings of the National Academy of Sciences, Vol. 105, Issue 10, p. 3678-3683 https://doi.org/10.1073/pnas.0712332105	journal	March 2008
Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis Woo, Hin-Koon; Northen, Trent R.; Yanes, Oscar Nature Protocols, Vol. 3, Issue 8 https://doi.org/10.1038/nprot.2008.110	journal	July 2008

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