SciTech Connect

Title: Oleoresin Capsicum toxicology evaluation and hazard review

Oleoresin Capsicum toxicology evaluation and hazard review Oleoresin Capsicum (OC) is an extract of the pepper plant used for centuries as a culinary spice (hot peppers). This material has been identified as a safe and effective Less-Than- Lethal weapon for use by Law enforcement and security professionals against assault. The National Institute of Justice (NIJ) is currently also evaluating its use in conjunction with other Less-Than-Lethal agents such as aqueous foam for use in corrections applications. Therefore, a comprehensive toxicological review of the literature was performed for the National Institute of Justice Less-Than-Lethal Force program to review and update the information available on the toxicity and adverse health effects associated with OC exposure. The results of this evaluation indicate that exposure to OC can result in dermatitis, as well as adverse nasal, pulmonary, and gastrointestinal effects in humans. The primary effects of OC exposure include pain and irritation of the mucous membranes of the eyes, nose, and lining of the mouth. Blistering and rash have been shown to occur after chronic or prolonged dermal exposure. Ingestion of capsicum may cause acute stinging of the lips, tongue, and oral mucosa and may lead to vomiting and diarrhea with large doses. OC vapors may also cause significant pulmonary irritation more » and prolonged cough. There is no evidence of long term effects associated with an acute exposure to OC, and extensive use as a culinary additive and medicinal ointment has further provided no evidence of long term adverse effects following repeated or prolonged exposure. « less
Authors:
Publication Date:
OSTI Identifier:OSTI ID: 120857
Report Number(s):SAND--95-2129
ON: DE96001765; TRN: 95:007860
DOE Contract Number:AC04-94AL85000
Resource Type:Technical Report
Resource Relation:Other Information: PBD: Oct 1995
Research Org:Sandia National Labs., Albuquerque, NM (United States)
Sponsoring Org:USDOE, Washington, DC (United States)
Country of Publication:United States
Language:English
Subject: 55 BIOLOGY AND MEDICINE, BASIC STUDIES; MEDICINAL PLANTS; EVALUATION; OLEORESINS; TOXICITY; PEPPERS; CHEMICAL COMPOSITION