Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation
- Helsinki
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- FOREIGN
- OSTI ID:
- 1194216
- Journal Information:
- Nature, Vol. 519, Issue 03, 2015
- Country of Publication:
- United States
- Language:
- ENGLISH
Similar Records
SGX393 inhibits the CML mutant Bcr-Abl[superscript T315I] and preempts in vitro resistance when combined with nilotinib or dasatinib
AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
Expression of BCR-ABL1 oncogene relative to ABL1 gene changes overtime in chronic myeloid leukemia
Journal Article
·
Tue Jan 12 00:00:00 EST 2010
· Proc. Natl. Acad. Sci. USA
·
OSTI ID:1194216
+10 more
AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
Journal Article
·
Tue Sep 07 00:00:00 EDT 2010
· Cancer Cell
·
OSTI ID:1194216
+24 more
Expression of BCR-ABL1 oncogene relative to ABL1 gene changes overtime in chronic myeloid leukemia
Journal Article
·
Fri Feb 15 00:00:00 EST 2008
· Biochemical and Biophysical Research Communications
·
OSTI ID:1194216
+4 more