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Title: Target molecules detection by waveguiding in a photonic silicon membrane

Patent ·
OSTI ID:1175010

Disclosed herein is a photonic silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls selectively bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and determine the concentration of bound target.

Research Organization:
Univ. of California, Oakland, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
W-7405-ENG-48
Assignee:
University Of California, The Regents Of
Patent Number(s):
6,785,432
Application Number:
10/159,175
OSTI ID:
1175010
Country of Publication:
United States
Language:
English

References (4)

The Physics of Macropore Formation in Low Doped n-Type Silicon journal January 1993
Silicon-Based Photonic Crystals journal March 2001
Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel journal March 2001
Nanotubule-Based Molecular-Filtration Membranes journal October 1997