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Title: Compositions, devices and methods for SERS and LSPR

Patent ·
OSTI ID:1117699

The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax).

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-03ER15457; W-31-109-ENG-38; AC02-06CH11357
Assignee:
Northwestern University (Evanston, IL)
Patent Number(s):
8,628,727
Application Number:
11/846,352
OSTI ID:
1117699
Resource Relation:
Patent File Date: 2007 Aug 28
Country of Publication:
United States
Language:
English

References (28)

Surface-enhanced raman nanobiosensor patent-application September 2004
Adaptive metal films for detection of biomolecules patent-application November 2005
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Localized Surface Plasmon Resonance Nanosensor:  A High-Resolution Distance-Dependence Study Using Atomic Layer Deposition journal November 2005
Vibrational spectra and structure of crystalline dipicolinic acid and calcium dipicolinate trihydrate journal January 1980
Octadecylthiol-modified surface-enhanced Raman spectroscopy substrates: a new method for the detection of aromatic compounds journal October 1992
Reagentless Identification of Single Bacterial Spores in Aqueous Solution by Confocal Laser Tweezers Raman Spectroscopy journal February 2004
Metal Film over Nanosphere (MFON) Electrodes for Surface-Enhanced Raman Spectroscopy (SERS):  Improvements in Surface Nanostructure Stability and Suppression of Irreversible Loss journal January 2002
Introductory Lecture : Surface enhanced Raman spectroscopy: new materials, concepts, characterization tools, and applications journal January 2006
Low-Level Detection of Viral Pathogens by a Surface-Enhanced Raman Scattering Based Immunoassay journal October 2005
Viscous flow reactor with quartz crystal microbalance for thin film growth by atomic layer deposition journal August 2002
Rapid Dipicolinic Acid Extraction from Bacillus Spores Detected by Surface-Enhanced Raman Spectroscopy journal March 2004
Detection of the Dipicolinic Acid Biomarker in Bacillus Spores Using Curie-Point Pyrolysis Mass Spectrometry and Fourier Transform Infrared Spectroscopy journal January 2000
Plasmon-Sampled Surface-Enhanced Raman Excitation Spectroscopy journal July 2003
Nanosphere lithography: A materials general fabrication process for periodic particle array surfaces
  • Hulteen, John C.; Van Duyne, Richard P.
  • Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films, Vol. 13, Issue 3, p. 1553-1558 https://doi.org/10.1116/1.579726
journal May 1995
Discrimination of Bacteria Using Surface-Enhanced Raman Spectroscopy journal January 2004
Sticking Probabilities in Adsorption of Alkanethiols from Liquid Ethanol Solution onto Gold journal November 2000
Sticking Probabilities in Adsorption from Liquid Solutions: Alkylthiols on Gold journal May 2000
Performance Assessment of Three Commercial Assays for Direct Detection of Bacillus anthracis Spores journal July 2003
Surface-Enhanced Raman Scattering Detected Temperature Programmed Desorption:  Optical Properties, Nanostructure, and Stability of Silver Film over SiO 2 Nanosphere Surfaces journal July 2001
Wavelength-Scanned Surface-Enhanced Raman Excitation Spectroscopy journal June 2005
Detection of Nitrate and Sulfate Anions by Normal Raman Spectroscopy and SERS of Cationic-Coated, Silver Substrates journal August 2000
Enhanced spore detection using dipicolinate extraction techniques journal March 2002
Electromagnetic Mechanism of Surface-Enhanced Spectroscopy book June 2006
Identification of Bacterial Spores Using Statistical Analysis of Fourier Transform Infrared Photoacoustic Spectroscopy Data journal August 2003
A Glucose Biosensor Based on Surface-Enhanced Raman Scattering:  Improved Partition Layer, Temporal Stability, Reversibility, and Resistance to Serum Protein Interference journal January 2004
An electrochemical surface-enhanced Raman spectroscopy approach to anthrax detection
  • Zhang, Xiaoyu; Yonzon, Chanda R.; Van Duyne, Richard P.
  • Optical Science and Technology, SPIE's 48th Annual Meeting, SPIE Proceedings https://doi.org/10.1117/12.508519
conference November 2003
Rapid Detection of an Anthrax Biomarker by Surface-Enhanced Raman Spectroscopy journal March 2005

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