skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Highly stable beta-class carbonic anhydrases useful in carbon capture systems

Patent ·
OSTI ID:1092751

The present disclosure relates to .beta.-class carbonic anhydrase polypeptides having improved properties including increased thermostability and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides formulations and uses of the polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering. Also provided are polynucleotides encoding the carbonic anhydrase polypeptides and host cells capable of expressing them.

Research Organization:
Codexis, Inc. (Redwood City, CA)
Sponsoring Organization:
USDOE
DOE Contract Number:
AR0000071
Assignee:
Codexis, Inc. (Redwood City, CA)
Patent Number(s):
8,512,989
Application Number:
13/721,586
OSTI ID:
1092751
Country of Publication:
United States
Language:
English

References (43)

A carbonic anhydrase from the archaeon Methanosarcina thermophila. journal July 1994
Gas Liquid Contactor and Effluent Cleaning System and Method patent-application January 2010
Process and apparatus for the treatment of carbon dioxide with carbonic anhydrase patent February 2003
Electrometric and Colorimetric Determination of Carbonic Anhydrase journal October 1948
Novel enzyme compositions for removing carbon dioxide from a mixed gas patent-application January 2008
Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Muller cells, and astrocytes journal May 2005
Ultra cleaning of combustion gas including the removal of CO2 patent January 2010
Chilled ammonia process for CO2 capture journal March 2010
PROCESS FOR ACCELERATED CAPTURE OF CARBON DIOXIDE patent-application April 2010
Role of Arginine 59 in the γ-Class Carbonic Anhydrases journal December 2001
Promoter enhanced chilled ammonia based system and method for removal of CO2 from flue gas stream patent January 2011
Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity journal November 2008
Triphasic process for gas effluent treatment patent August 2009
Carbonic Anhydrase in the Scleractinian Coral Stylophora pistillata journal September 2008
A Structure−Function Study of a Proton Transport Pathway in the γ-Class Carbonic Anhydrase from Methanosarcina thermophila journal August 2000
Treatment unit for treating a fluid and method thereof patent November 2002
Determinants of catalytic activity and stability of carbonic anhydrase II as revealed by random mutagenesis. journal January 1993
Purification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers journal December 2000
Triphasic bioreactor and process for gas effluent treatment patent October 2010
CO2 absorption solution patent June 2010
Evolution of carbonic anhydrases in fungi journal March 2009
Methods, apparatuses, and reactors for gas separation patent-application January 2007
Process and a plant for the production of Portland cement clinker patent June 2005
CO 2 Capture by Means of an Enzyme-Based Reactor journal March 2003
Carbonic anhydrase is an ancient enzyme widespread in prokaryotes journal December 1999
Process for immobilization of protein catalysts, product, and use patent January 2010
A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila. journal May 1996
Triphasic bioreactor and process for gas effluent treatment patent February 2007
CO2 hydration by immobilized carbonic anhydrase journal October 2003
Enzyme systems for gas processing patent November 2000
Kinetic and Spectroscopic Characterization of the Gamma-Carbonic Anhydrase from the Methanoarchaeon Methanosarcina thermophila journal October 1999
Spray Process For The Recovery Of CO2 From A Gas Stream And A Related Apparatus May 2011
Characterization of heterologously produced carbonic anhydrase from Methanosarcina thermophila journal June 1996
Carbonic anhydrase having increased stability under high temperature conditions patent April 2009
Heat-stable carbonic anhydrases and their use patent September 2010
CO2 ABSORPTION SOLUTION patent-application August 2010
Method and apparatus for the removal of carbon dioxide from a gas stream patent June 2011
Method for Removing Carbon Dioxide from Fluid Flows, in Particular Combustion Exhaust Gases patent-application September 2010
Sequestration of carbon dioxide patent November 2006
Process and a plant for recycling carbon dioxide emissions from power plants into useful carbonated species patent October 2009
A Closer Look at the Active Site of γ-Class Carbonic Anhydrases:  High-Resolution Crystallographic Studies of the Carbonic Anhydrase from Methanosarcina thermophila , journal August 2000
Process and installation for the fractionation of air into specific gases patent April 2009
A Plant-Type (β-Class) Carbonic Anhydrase in the Thermophilic Methanoarchaeon Methanobacterium thermoautotrophicum journal October 1999