Identification of genetic modifiers of susceptibility to radiation-induced lymphoma
- University of California, San Francisco, CA (United States)
The specific aims of this project were as follows: Aim 1: Identify mouse genetic loci that affect the survival time of mice post radiation. Aim 2: Identify somatic genetic alterations that are indicative of tumor suppressor and oncogene loci involved in radiation-induced cancers. Aim 3: Identify candidate radiation susceptibility genes by gene expression microarray analysis of the radiation response in normal tissues or in tumors from the strains used for aims 1 and 2.
- Research Organization:
- Univ. of California, San Francisco, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FG02-03ER63630
- OSTI ID:
- 1086517
- Report Number(s):
- Final Progress Report
- Country of Publication:
- United States
- Language:
- English
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