Three Hydrogen Bond Donor Catalysts: Oxyanion Hole Mimics and Transition State Analogues
Journal Article
·
· Journal of the American Chemical Society, 134(45):18534-18537
Enzymes and their mimics use hydrogen bonds to catalyze chemical transformations. Small molecule transition state analogs of oxyanion holes are characterized by gas phase IR and photoelectron spectroscopy and their binding constants in acetonitrile. As a result, a new class of hydrogen bond catalysts is proposed (OH donors that can contribute three hydrogen bonds to a single functional group) and demonstrated in a Friedel-Crafts reaction.
- Research Organization:
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 1059186
- Report Number(s):
- PNNL-SA-88858; 44678; 42590; KC0301020
- Journal Information:
- Journal of the American Chemical Society, 134(45):18534-18537, Journal Name: Journal of the American Chemical Society, 134(45):18534-18537
- Country of Publication:
- United States
- Language:
- English
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