A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots
- Vanderbilt Univ., Nashville, TN (United States). Dept. of Chemistry
- Vanderbilt Univ., Nashville, TN (United States). Dept. of Chemistry; Inst. for Nanoscale Science and Engineering, Nashville, TN (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science & Technology Division
Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs). Our anticipation is that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators.
- Research Organization:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC)
- DOE Contract Number:
- AC05-00OR22725
- OSTI ID:
- 1049125
- Journal Information:
- ChemComm, Vol. 48, Issue 44; ISSN 1359-7345
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
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