VESPA: Software to Facilitate Genomic Annotation of Prokaryotic Organisms Through Integration of Proteomic and Transcriptomic Data

Journal Article · Wed Apr 25 00:00:00 EDT 2012 · BMC Genomics, 13(1):Article No. 131

DOI:https://doi.org/10.1186/1471-2164-13-131· OSTI ID:1043111

Peterson, Elena S.; McCue, Lee Ann; Rutledge, Alexandra C.; Jensen, Jeffrey L.; Walker, Julia; Kobold, Mark A.; Webb, Samantha R.; Payne, Samuel H.; Ansong, Charles; Adkins, Joshua N.; Cannon, William R.; Webb-Robertson, Bobbie-Jo M.

Visual Exploration and Statistics to Promote Annotation (VESPA) is an interactive visual analysis software tool that facilitates the discovery of structural mis-annotations in prokaryotic genomes. VESPA integrates high-throughput peptide-centric proteomics data and oligo-centric or RNA-Seq transcriptomics data into a genomic context. The data may be interrogated via visual analysis across multiple levels of genomic resolution, linked searches, exports and interaction with BLAST to rapidly identify location of interest within the genome and evaluate potential mis-annotations.

• Research Organization: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• OSTI ID: 1043111
• Report Number(s): PNNL-SA-82717; 600306000
• Journal Information: BMC Genomics, 13(1):Article No. 131, Vol. 13, Issue 1
• Country of Publication: United States
• Language: English