skip to main content

SciTech Connect

Title: Detection of BCR-ABL Fusion mRNA Using Reverse Transcriptase Loop-mediated Isothermal Amplification

RT-PCR is commonly used for the detection of Bcr-Abl fusion transcripts in patients diagnosed with chronic myelogenous leukemia, CML. Two fusion transcripts predominate in CML, Br-Abl e13a2 and e14a2. They have developed reverse transcriptase isothermal loop-mediated amplification (RT-LAMP) assays to detect these two fusion transcripts along with the normal Bcr transcript.
Authors:
; ; ; ; ;
Publication Date:
OSTI Identifier:
1034502
Report Number(s):
LLNL-TR-520096
TRN: US201204%%46
DOE Contract Number:
W-7405-ENG-48
Resource Type:
Technical Report
Research Org:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; AMPLIFICATION; DETECTION; LEUKEMIA; MYELOID LEUKEMIA; PATIENTS