NHC-Catalyzed/Titanium(IV);#8722;Mediated Highly Diastereo- and Enantioselective Dimerization of Enals
- NWU
An NHC-catalyzed, diastereo- and enantioselective dimerization of enals has been developed. The use of Ti(Oi-Pr){sub 4} is a key element for the reactivity and selectivity of this process. The cyclopentenes are obtained with high levels of diastereo- and enantioselectivity and their synthetic utility is demonstrated by functionalization of the product alkene.
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- NIHINDUSTRY
- OSTI ID:
- 1031942
- Journal Information:
- Org. Lett., Vol. 13, Issue (5) ; 04, 2011; ISSN 1523-7060
- Country of Publication:
- United States
- Language:
- ENGLISH
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