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Title: BioCARS: a synchrotron resource for time-resolved X-ray science

Abstract

BioCARS, a NIH-supported national user facility for macromolecular time-resolved X-ray crystallography at the Advanced Photon Source (APS), has recently completed commissioning of an upgraded undulator-based beamline optimized for single-shot laser-pump X-ray-probe measurements with time resolution as short as 100 ps. The source consists of two in-line undulators with periods of 23 and 27 mm that together provide high-flux pink-beam capability at 12 keV as well as first-harmonic coverage from 6.8 to 19 keV. A high-heat-load chopper reduces the average power load on downstream components, thereby preserving the surface figure of a Kirkpatrick-Baez mirror system capable of focusing the X-ray beam to a spot size of 90 {micro}m horizontal by 20 {micro}m vertical. A high-speed chopper isolates single X-ray pulses at 1 kHz in both hybrid and 24-bunch modes of the APS storage ring. In hybrid mode each isolated X-ray pulse delivers up to {approx}4 x 10{sup 10} photons to the sample, thereby achieving a time-averaged flux approaching that of fourth-generation X-FEL sources. A new high-power picosecond laser system delivers pulses tunable over the wavelength range 450-2000 nm. These pulses are synchronized to the storage-ring RF clock with long-term stability better than 10 ps RMS. Monochromatic experimental capability with Biosafety Levelmore » 3 certification has been retained.« less

Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;  [1]
  1. NIH
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
DOE - BASIC ENERGY SCIENCESNIH
OSTI Identifier:
1022264
Resource Type:
Journal Article
Journal Name:
J. Synchrotron Rad.
Additional Journal Information:
Journal Volume: 18; Journal Issue: (4) ; 07, 2011; Journal ID: ISSN 0909-0495
Country of Publication:
United States
Language:
ENGLISH
Subject:
43 PARTICLE ACCELERATORS; ADVANCED PHOTON SOURCE; COMMISSIONING; CRYSTALLOGRAPHY; FOCUSING; LASERS; MIRRORS; OPTICS; PHOTONS; STABILITY; SYNCHROTRONS; TIME RESOLUTION; WAVELENGTHS; WIGGLER MAGNETS

Citation Formats

Graber, T, Anderson, S, Brewer, H, Chen, Y -S, Cho, H, Dashdorj, N, Henning, R W, Kosheleva, I, Macha, G, Meron, M, Pahl, R, Ren, Z, Ruan, S, Schotte, F, Srajer, V, Viccaro, P J, Westferro, F, Anfinrud, P, Moffat, K, and UC). BioCARS: a synchrotron resource for time-resolved X-ray science. United States: N. p., 2011. Web. doi:10.1107/S0909049511009423.
Graber, T, Anderson, S, Brewer, H, Chen, Y -S, Cho, H, Dashdorj, N, Henning, R W, Kosheleva, I, Macha, G, Meron, M, Pahl, R, Ren, Z, Ruan, S, Schotte, F, Srajer, V, Viccaro, P J, Westferro, F, Anfinrud, P, Moffat, K, & UC). BioCARS: a synchrotron resource for time-resolved X-ray science. United States. https://doi.org/10.1107/S0909049511009423
Graber, T, Anderson, S, Brewer, H, Chen, Y -S, Cho, H, Dashdorj, N, Henning, R W, Kosheleva, I, Macha, G, Meron, M, Pahl, R, Ren, Z, Ruan, S, Schotte, F, Srajer, V, Viccaro, P J, Westferro, F, Anfinrud, P, Moffat, K, and UC). 2011. "BioCARS: a synchrotron resource for time-resolved X-ray science". United States. https://doi.org/10.1107/S0909049511009423.
@article{osti_1022264,
title = {BioCARS: a synchrotron resource for time-resolved X-ray science},
author = {Graber, T and Anderson, S and Brewer, H and Chen, Y -S and Cho, H and Dashdorj, N and Henning, R W and Kosheleva, I and Macha, G and Meron, M and Pahl, R and Ren, Z and Ruan, S and Schotte, F and Srajer, V and Viccaro, P J and Westferro, F and Anfinrud, P and Moffat, K and UC)},
abstractNote = {BioCARS, a NIH-supported national user facility for macromolecular time-resolved X-ray crystallography at the Advanced Photon Source (APS), has recently completed commissioning of an upgraded undulator-based beamline optimized for single-shot laser-pump X-ray-probe measurements with time resolution as short as 100 ps. The source consists of two in-line undulators with periods of 23 and 27 mm that together provide high-flux pink-beam capability at 12 keV as well as first-harmonic coverage from 6.8 to 19 keV. A high-heat-load chopper reduces the average power load on downstream components, thereby preserving the surface figure of a Kirkpatrick-Baez mirror system capable of focusing the X-ray beam to a spot size of 90 {micro}m horizontal by 20 {micro}m vertical. A high-speed chopper isolates single X-ray pulses at 1 kHz in both hybrid and 24-bunch modes of the APS storage ring. In hybrid mode each isolated X-ray pulse delivers up to {approx}4 x 10{sup 10} photons to the sample, thereby achieving a time-averaged flux approaching that of fourth-generation X-FEL sources. A new high-power picosecond laser system delivers pulses tunable over the wavelength range 450-2000 nm. These pulses are synchronized to the storage-ring RF clock with long-term stability better than 10 ps RMS. Monochromatic experimental capability with Biosafety Level 3 certification has been retained.},
doi = {10.1107/S0909049511009423},
url = {https://www.osti.gov/biblio/1022264}, journal = {J. Synchrotron Rad.},
issn = {0909-0495},
number = (4) ; 07, 2011,
volume = 18,
place = {United States},
year = {Tue Aug 16 00:00:00 EDT 2011},
month = {Tue Aug 16 00:00:00 EDT 2011}
}