Columnar DNA superlattices in lamellar O-ethylphosphatidylcholine lipoplexes. Mechanism of the gel-liquid crystalline lipid phase transition
- NWU
DNA arranges into rectangular columnar superlattices between interdigitated lipid bilayers in the low-temperature gel phase of the lipoplexes of the cationic o-ethylphosphatidylcholines. The interlamellar correlation in the DNA ordering is not observed within the liquid crystalline lipid phase. The gel-liquid crystalline phase transition of the lipid induces a contraction of the DNA smectic array that matches the increased positive charge density of the membrane surface caused by the interdigitated-noninterdigitated transition. The transition proceeds via an intermediate state that has an expanded lamellar repeat period.
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 1008701
- Journal Information:
- Nano Lett., Vol. 4, Issue (8) ; 08, 2004; ISSN 1530-6984
- Country of Publication:
- United States
- Language:
- ENGLISH
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